https://doi.org/10.1530/JOE-20-0590https://joe.bioscientifica.com © 2021 Society for EndocrinologyPrinted in Great BritainPublished by Bioscientifica Ltd.Journal of Endocrinology248:3 R99–R112 J Chen and J E Gunton Islet transplantationREVIEWBeta-cell function and human islet transplantation: ca...
Others have found that serum IGF-1 correlates with residual beta cell function, a correlation the UAB researchers also found for the verapamil group, as measured by retention of the ability to produce endogenous insulin by the beta cells that are located in pancreatic islets. RNA sequencing of s...
Diet-induced weight loss is associated with improved beta-cell function in people with type 2 diabetes (T2D) with remaining secretory capacity. It is unknown if adding exercise to diet-induced weight loss improves beta-cell function and if exercise volume is important for improving beta-cell funct...
Preservation of β-cell function by targeting β-cell mass Type 2 diabetes is characterized by progressive β-cell dysfunction and a reduction in β-cell mass. Pancreatic islets are a target for adverse effectors s... EJPD Koning,S Bonner-Weir,TJ Rabelink - 《Trends in Pharmacological ...
The pathways that control insulin secretion and regulate pancreatic beta-cell mass are crucial in the development of diabetes mellitus. Maturity-onset diabetes of the young comprises a number of single-gene disorders affecting pancreatic beta-cell function, and the consequences of mutations in these ge...
A role for CFTR in [beta]-cell functionJoana Osorio
Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes View LargeDownload Figure 1. Recruitment, Randomization, and Follow-up of Participants in a Trial of Verapamil vs Placebo for the Preservation of Beta Cell Function in Children and Adolescents With ...
Other articles where beta cell is discussed: islets of Langerhans: …which the major types (alpha, beta, delta, and pancreatic polypeptide [PP] cells) produce important hormones. The two minor types (D1 and enterochromaffin cells) produce hormones and sy
We estimated the heritability of individual differences in beta cell function after a mixed meal test designed to assess a wide range of classical and model-derived beta cell function parameters. A total of 183 healthy participants (77 men), recruited from the Netherlands Twin Register, took part...
et al. MicroRNA-7a regulates pancreatic beta cell function. J. Clin. Invest. 124, 2722–2735 (2014). Article CAS PubMed PubMed Central Google Scholar Kameswaran, V. et al. Epigenetic regulation of the DLK1–MEG3 microRNA cluster in human type 2 diabetic islets. Cell Metab. 19, 135...