Higher resting heart rate (HR) has been shown to be an independent cardiovascular risk factor. However, some retrospective studies suggest that beta-blockers (BBs)-associated reduction in HR worsens left atrial (LA) function and increases the risk of stroke in hypertensive patients.#Purpose: to ...
September 15, 2009 (London, United Kingdom)— A new analysis of the Anglo-Scandinavian Cardiac Outcomes Trial--Blood Pressure Lowering Arm (ASCOT-BPLA) shows that the amlodipine (Norvasc, Pfizer)-based arm of the study remained superior to the beta-blocker arm, even when resting heart rate ...
Meta-analysis: beta-blocker dose, heart rate reduction, and death in patients with heart failure. Ann Intern Med. 2009;150:784–94. Article PubMed Google Scholar Böhm M, Swedberg K, Komajda M, Borer JS, Ford I, Dubost-Brama A, et al. Heart rate as a risk factor in chronic ...
This study aimed to compare whether reduced heart rate (HR) or higher beta-blocker (BB) dose affected outcomes to a greater extent in the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial population. Recent data have shown that HR is an important ...
Mr. Martin is suffering from a condition known as ventricular tachycardia, in which his heart beats too quickly. Would an alpha-blocker or a beta-blocker help alleviate his problem? Why? How does the rate of blood flow in and the rate of blood flow out of the right atrium effe...
Beta-blockers in heart failure with preserved ejection fraction: a meta-analysis Beta-blockers are established drugs in heart failure with reduced ejection fraction, but their role in heart failure with preserved ejection fraction (HFpE... C Bavishi,S Chatterjee,S Ather,... - 《Heart Failure ...
Effects of Beta-Blockers on the Relation Between QT Interval and Heart Rate in Survivors of Acute Myocardial Infarction doi:10.1111/j.1542-474X.1998.tb00040.xAnnals of Noninvasive ElectrocardiologyHintze, UlrikWüpper, FinnMickley, HansMφller, Mogens...
β-受体阻滞剂(Beta blocker)第一节 6 - 受体阻滞剂 6 - adrenergic block agents 本类药物可竞争性地与β受体结合而产生拮抗神经递质或β激动剂效应, 主要包括对心脏的兴奋作用盒对支气管及血管平滑肌的舒张 作用等.可使心率减慢、心肌收缩力减弱、心输出量减少、心肌耗氧下降, 还能延缓心房和房室结的传导....
Beta blockers inhibit these normal epinephrine-mediated sympathetic actions, but have minimal effect on resting subjects. That is, they reduce the effect of excitement/physical exertion on heart rate and force of contraction, dilation of blood vessels and opening of bronchi, and also reduce tremor ...
abeta blocker; beta-adrenergic inhibitor that slows heart rate and decreases cardiac contractility and cardiac output, thereby lowering blood pressure; beta blockers are less effective in African Americans than they are in Caucasians; the same is true for angiotensin-converting enzyme (ACE) inhibitors...