β-Arrestins regulate a Ral-GDS-Ral effector pathway that mediates cytoskeletal reorganization. Nat Cell Biol 4, 547-555.Bhattacharya, M., P. H. Anborgh, A. V. Babwah, L. B. Dale, T. Dobransky, J. L. Benovic, R. D. Feldman, J. M. Verdi, R. J. Rylett, and S. S. G....
Activation of the AT1 receptor-beta-arrestin signaling pathway inhibits NHE3 activity in the renal proximal tubulePhys iology -Regulation of Epithelial Trans porters , Paracellular Transport, and Regulatory Proteins : Activation of the AT1 rec eptor-beta-arres tin s ignaling pathway inhibits N H ...
(GPCR) signaling. More recently, beta -Arrestins have been determined to serve as scaffolds for various signaling pathways, including the MAPK cascades activating ERK2, p38 alpha, and JNK3. These beta -Arrestin scaffolds tie together the appropriate kinases in series, forming a discreet signaling...
Beta Arrestin 2 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA Cat No. 10171-1-AP 引用文献(27) 宿主/亚型 Rabbit / IgG 种属反应性 human, mouse, rat and More (2) 应用 WB, IHC, IF/ICC, ELISA and More (3) 别名 ARRB2, β-Arrestin 2, Beta-arrestin-2, BARR2, Arrestin beta...
J. Ogasawara, M. Sanpei, N. Rahman et al., "𝛽-adrenergic recep- tor trafficking by exercise in rat adipocytes: roles of G-protein- coupled receptor kinase-2, 𝛽-arrestin-2, and the ubiquitin- proteasome pathway," The FASEB Journal, vol. 20, no. 2, pp. 350- 352, 2006....
Then, GPCRs can be divided into two classes, A and B: class A receptors have low affinity with beta-arrestins and consequently detach from this complex very quickly, being recycled back to the plasma membrane after internalization (i.e.: β2AR). In the other hand, Class B receptors ...
7 Other β-arrestin-Dependent Behavior 7.1 Cannabinoid receptors Studies indicate that β-arrestin negatively regulates cannabinoid CB1 receptor functions.156Δ9-Tetrahydrocannabinol (Δ9-THC) and CP55,940, two CB1 receptor agonists, induce antinociception and decrease in body temperature in mice. While...
is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway. Also known as: Anti-Phospho-beta-Arrestin 1 (Ser412)抗体beta Arrestin 1 (phospho S412); p-beta Arrestin 1 (phospho S412); ARB 1; ARB1; ARR 1; ARR1; AR...
diet induced thermogenesis vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure desensitization of G-protein coupled receptor protein signaling pathway by arrestin diaphragm contraction positive regulation of the force of heart contraction by epinephrine receptor-medi...
for the arrestin pathway in HEK293 cells11,44. Again, this effect was not driven by arrestins (Fig.5eand Supplementary Fig.7a, b) but entirely depended on G proteins (Fig.5f). Similar findings were obtained for V2R, another GPCR described by some as prototypal for arrestin-dependent, G...