" says Howard Parnes, MD, chief of the prostate and urologic cancer research group in the Division of Cancer Prevention for the National Cancer Institute in Bethesda,Maryland."About 95% of men with a Gleason score of 6 are treated with radiation or surgery—we know that repres...
Genetic profiling of Gleason grade 4/5 prostate cancer: which is the best pro- static control tissue? J Urol 2003;170:2263-8.Stamey TA,Caldwell MC,Fan Z. Genetic profiling of Gleason grade 4/5 prostate cancer:which is the best prostatic control tissue[J].Journal of D Urologie,2003,(6 ...
In the setting of Gleason score 4+3 or 4+4=8 cancer on at least 1 part, the extent of high-grade cancer could affect clinical treatment such that workup of other atypical possible high-grade cancer foci is justified. In the setting of Gleason score 4+3 or higher-grade cancer on at ...
Only about 7% to 10% of men who present with prostate cancer have disease of Gleason score 9 or 10. Nevertheless, investigators from 12 tertiary care centers in the United States and one in Norway analyzed 1809 patients who had received treatment for prostate cancer of Gleason score 9 or 10...
Introduction Management of prostate cancer was revolutionized by the discovery of prostate specific antigen. While prostate specific antigen is an excellent biomarker for followup after treatment, it has low specificity as a screening test and most biopsies are negative when prompted by elevated prostate...
cancer compared to men who had a negative biopsy. (The Gleason Score is a grading system used to determine the aggressiveness of prostate cancer.) A score of 6 is generally considered low-risk cancer recommended for active surveillance, while a score of 7 or more may require radiation or ...
However, the surgery for localized low-risk prostate cancer may not be the standard anymore due to the concern of overtreatment recently. On the other hand, regarding the treatment of high-risk or locally advanced prostate cancer, the role of surgery started to extend their territory....
The carcinoma of the prostate is the most common cancer among European males, with an estimate of 470,000 cases in 2020 [1]. Radical prostatectomy (RP) as a typical treatment has evolved over the past decades, nowadays offering a high standard of therapy through minimally invasive and robot-...
New Orleans-It’s been said that the best treatment for low-risk prostate cancer is no treatment at all. A number of studies at the 2015 AUA annual meeting appeared to bear that out, showing active surveillance to be a safe and increasingly common approach in this patient population. ...
Eligible men were initially diagnosed with low-risk PCa (clinical stage <= T2, prostate-specific antigen [PSA] <= 10 ng/ml, PSA density <0.2 ng/ml per ml, one or two positive biopsy cores, and Gleason score <= 6) and underwent RP between December 2006 and July 2011. The study ...