He has special interest in the treatment of brain tumours like Gliomas, Glioblastomas and benign tumours like Meningiomas and Schwannomas. He keeps adding to his skills by attending conferences and publishing articles in various national and international journals. He is also on the editorial board ...
We performed a treatment-based analysis of data from the pivotal phase III trial of the NovoTTF-100A System™ versus best physician’s choice (BPC) chemotherapy in patients with recurrent glioblastoma multiforme (GBM), with particular focus on efficacy in patients using NovoTTF Therapy as ...
In addition, ibrutinib (Imbruvica, Pharmacyclics), already in use in the second-line treatment of CLL, is the subject of a phase 3 trial in the first-line setting. Ibrutinib has been repeatedly called "transformative" and "game-changing" in CLL because of unprecedented response rates in patien...
The antipsychotic treatment has been at the center of a couple of different controversies that may bring its useful life to even more of a halt. In the early 2000s, the FDA’s office of criminal investigation claimed Eli Lilly was promoting off-label usage of the drug, meaning it...
By his later years, Kennedy had come to be viewed as a major figure and spokesman for American progressivism. On August 25, 2009, Kennedy died of a brain tumor (glioblastoma) at his home in Hyannis Port, Massachusetts, at the age of 77. He was buried at Arlington National Cemetery....
From 65 to 70 years old: what is the best approach in the treatment of glioblastoma?doi:10.18203/2349-3933.IJAM20214513Joo UlrichDiogo DelgadoAndré FigueiredoMiguel SimasMaria Eduarda NevesJoana PiscoManuel Carmo da SilvaAndré Abrunhosa Branquinho...
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity ofMGMTpromoter methylated glioblastoma Nina Struve Zev A. Binder Malte Kriegs ArticleOpen Access17 Feb 2020Oncogene Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications ...
A phase 1 study to assess BDTX-1535, an oral EGFR inhibitor, in patients with glioblastoma or non–small-cell lung cancer. TPS9156#Background:The epidermal growth factor receptor (EGFR) is a potent oncogene commonly altered in many cancers, including glioblastoma (GBM) and non-... ML Johnso...
engineering methods. This astonishing scientific breakthrough allows the destruction of brain cancer cells but the researchers hope to expand the potency of their finding. The next goal is to develop a treatment for glioblastoma which would make the most lethal type of brain tumor a treatable ...