572 Berubicin, a topoisomerase II poison with high CNS uptake, inhibits cell growth and induces apoptosis in diffuse large B-cell lymphomasautomotive industryindustrial policypolitical economybureaucracyadministrative guidancescale economiesThis article has no associated abstract. ( fix it )...
572 Berubicin, a topoisomerase II poison with high CNS uptake, inhibits cell growth and induces apoptosis in diffuse large B-cell lymphomasEUROPEAN JOURNAL OF CANCER -SUPPLEMENT-PriebeW.WangM.SunL.FoktI.BaoH.ZhangJayakumarA.
("CNSP") has licensed Berubicin and initiated a randomized, controlled clinical trial of Berubicin vs. Lomustine in adults with recurrent GBM after first line therapy. The primary endpoint of this study, being conducted in the United States and Europe, is overall survival (OS), with a ...
577 Berubicin, a novel mechanistically altered anthracycline potently inhibits cell growth and induces apoptosis in mantle cell lymphomaEUROPEAN JOURNAL OF CANCER -SUPPLEMENT-WangM.SunL.FoktI.BaoH.ZhangJayakumarA.PriebeW.
577 Berubicin, a novel mechanistically altered anthracycline potently inhibits cell growth and induces apoptosis in mantle cell lymphomaHumansBasal Ganglia DiseasesSulfonamidesPiperidinesDiazepamImipramineFluphenazinePalmitic AcidsAntiparkinson AgentsAntipsychotic Agents...
A current, potentially pivotal trial for patients with recurrent GBM after first-line therapy has completed enrollment in the US and Europe: a total of 252 patients were randomized 2:1 (Berubicin:Lomustine) after failure of prior therapy. All patients had to have certification of progression ...
Berubicin is an analog of doxorubicin that appears to cross the BBB with significant central nervous system (CNS) uptake. A pivotal trial for patients with recurrent glioblastoma (GBM) after first-line therapy has finished enrollment with 252 patients in the US and Europe with evidence of ...
600 POSTER Hematologic pharmacodynamics linked to the pharmacokinetics of berubicin (B), a blood–brain barrier penetrating anthracycline active against high grade glioma, in phase I/II clinical trials - ResearchGatedoi:10.1016/S1359-6349(08)72534-5R....
600 POSTER Hematologic pharmacodynamics linked to the pharmacokinetics of berubicin (B), a blood-brain barrier penetrating anthracycline active against high grade glioma, in phase I/II clinical trialsKazerooniR.ConradC.JohansenM.J.SakamotoM.