(b) benzyl alcohol in a weight ratio of approximately 1-4% (c) polysorbate 20 in a weight ratio of approximately 0.05-0.8%; and (d) an aqueous carrier. In an embodiment, the injectable pharmaceutical composition comprises: (a) aripiprazole, or olanzapine, or a compound of formula I, II...
Examples of rate-sustaining polymers include hydroxypropyl methylcellulose, hydroxypropyl cellulose, methyl cellulose, ethyl cellulose, sodium carboxymethyl cellulose, polyvinyl alcohol, polyvinyl pyrrolidone, xanthum gum, polymethacrylates, polyethylene oxide and polyethylene glycol. Liquid (including multiple ...
The alcohol is converted to the bromide 56, which may be used to alkylate a heterocyclic compound defined in Part I to afford an AII Antagonist of general Formula Ia-Ic. ##STR62## Substituted 4-hydroxybenzoic esters are also convenient precursors for the synthesis of the substituted benzyl ...
The compounds of formula (IV) may be synthesized in an analogous manner as set out in U.S. Pat. No. 5,354,861. A 3-keto-benzothiophene compound of formula (VI) ##STR10## may be condensed with the appropriate aldehyde in catalytic amounts of hydrochloric acid. ...
Typically cosmetic ingredients include, for example; water, ethyl alcohol, isopropyl alcohol, glycerin, glycerol propylene glycol, sorbitol and other high molecular weight alcohols. In addition, contraceptive compositions may contain minor amounts, e.g. from about 0.1 to 5% weight based on the ...
alcohol, and toluene. The oxidation of the imidazolines and the 3,4,5,6-tetrahydropyrimidines of formula IV wherein R1represents lower alkyl (or a functional equivalent thereof) is effected under conditions such as by subjecting the compounds to air while being heated (under reflux conditions)...