This new heterocyclic haloorganoamino-1,3-benzothiazole derivative, was a starting material, which condensed and tethered with three different aromatic aldehyde pendant arm in presence of ethanol and glacial acetic acid isolating an interesting sequence of tridentate Schiff bases 2...
This article describes the synthesis and the biological evaluation of two sets of benzothiazole derivatives bearing at C-2 an arylamide ( 1a – e , 2a – e ) or an arylurea ( 3a – d , 4a – d ) moiety. Five compounds ( 3d and 4a – d ) were selected and screened by the Natio...
Synthesis of Benzothiazole Benzothiazole is a conjugated sp2-hybridized bicyclic 10π electron heteroaromatic, constituted by fusion of benzene with the 4... Jan 24,2022Benzothiazole Basic information Product Name: Benzothiazole Synonyms: Benzothiazote;BENZOTHIAZOLE 96+%;Benzothiazole (6CI,8CI,9CI);Benz...
Design, Synthesis and Evaluation of Benzothiazole Derivatives as Multifunctional AgentsAntifungalAntioxidantAntiproliferativeBenzothiazolesUV-filterhERG channelsOxidative stress is the product or aetiology of various multifactorial diseases; on the other hand, the development of multifunctional compounds is a ...
benzothiazole derivativesbiological activityDespite improvements in survival rates, cancer and viral diseases remain the second leading cause of death in the western world. Therefore, an area of major pharmaceutical interest over the last several decades has been the development of small molecules with ...
It has great pharmaceutical importance; hence synthesis of this compound is of considerable interest.Methods: Various 3-(substituted phenyl)-1-(6-methyl-1,3-benzothiazol-2-yl)-1H-pyrazole-4-carbaldehyde deriva- tives (5a-g) were designed and synthesized starting from 4-methyl aniline. All ...
Synthesis and evaluation of some novel benzothiazole derivatives as potential anticancer and antimicrobial agents. Intensive efforts are underway worldwide to develop anticancer and antimicrobial agents. Therefore, a novel series of pyri-do[2,1-b]benzo[d]thiazole and 2-... AM Youssef,E Noaman - ...
A parent benzothiazole molecule was synthesized by Jacobson synthesis, then itis subjected to treatment with various aromatic aldehydes to get the corresponding Schiffbases followed by esterification of carboxyl group by using various alcohols. Thestructures of synthesized compounds were confirmed by various...
ChemInform Abstract: Synthesis and Antimicrobial Activity of Some New Thiazole, Thiophene and Pyrazole Derivatives Containing Benzothiazole Moiety. Starting from benzothiazole derivative (I) a series of new heterocyclic derivatives of type (IV), (VII), (X), (XII), and (XIV) containing the benzothiaz...
Synthesis of novel benzimidazole and benzothiazole derivatives bearing a 1,2,3-triazole ring system and their acetylcholinesterase inhibitory activity benzothiazole1,2,3-triazoleProtonation of the highly reactive 1:1 intermediate produced in the reaction between triphenylphosphine and an acetylenic ester by ...