Purification MethodsFree it from benzoic acid by washing with NaHCO3, then water, and drying. Crystallise it from *benzene (0.5mL/g) by adding just enough pet ether (b 40-60o) to cause cloudiness, then cool in ice. It can be distilled at 210-220o/20mm. [Beilstein 19 IV 550.] ...
PROCESS:The compound of formula (1a) is prepared by reacting 1mol of the compound of formula (2) with 1-1.5mol of the compound of formula (3) (X is Br, Cl or I) in a solvent such as methanol in the presence of an acid acceptor (e.g. NaHCO3). When the molar ratio of the ...
NaHCO3 solution (2 × 15 mL), H2O (2 × 15 mL), and brine (1 × 15 mL). The organic layer was dried over Na2SO4 and concentrated in vacuo. Purification by silica gel column chromatography (10% EtOAc–hexane) afforded the pure dihydro-1,4-dithiins and dihydro-1,4-dithianes. ...
PROCESS:The compound of formula (1a) is prepared by reacting 1mol of the compound of formula (2) with 1-1.5mol of the compound of formula (3) (X is Br, Cl or I) in a solvent such as methanol in the presence of an acid acceptor (e.g. NaHCO3). When the molar ratio of the ...
Keywords: aromatic hydroxylation; 2-iodoxybenzoic acid (IBX); lipophilic piceatannol derivatives; lipophilic antioxidants 1. Introduction In the last few years, stilbene-based compounds have attracted the attention of many researchers due to their wide range of positive biological effects [1–3]. One...