PROCESS:A halomethylcyclohexane of formula II (X is halogen) and an m-hydroxybenzoic acid amide derivative of formula III are heated at 50 deg.C- the refluxing temperature in the absence or presence of an organic solvent, e.g. toluene, with a dehydrohalogenating agent, e.g. Na2CO3, to ...
ARTICLE Received 4 Oct 2015 | Accepted 9 Dec 2015 | Published 27 Jan 2016 DOI: 10.1038/ncomms10443 OPEN Pd(II)-catalysed meta-C–H functionalizations of benzoic acid derivatives Shangda Li1,*, Lei Cai1,*, Huafang Ji1, Long Yang1 & Gang Li1,2 Benzoic acids are highly important ...
PREPARATION:A 2-phenoxyethyl halide shown by the formula II (Y is halogen) is reacted with a metahydroxybenzoic acid amide derivative shown by the formula III in the absence of a solvent or in an inert organic solvent such as toluene, xylene, etc. in the presence of a dehydrohalogenating...
annelationaromatic carboxylatesC−H activationrhodiumIn the presence of a [Cp*RhCl2]2 catalyst, the Lewis acid In(OTf)3 and the mild base Na2CO3, aromatic carboxylates and α,β澆爑rated ketones undergo a unique hydroarylation/Claisen/retro〤laisen process to give the corresponding indanone...
annelationaromatic carboxylatesC−H activationrhodiumIn the presence of a [Cp*RhCl2]2 catalyst, the Lewis acid In(OTf)3, and the mild base Na2CO3, aromatic carboxylates and α,β‐unsaturated ketones undergo a unique hydroarylation/Claisen/retro‐Claisen process to give the corresponding ...
Method provides increase of benzoic acid yield from 12.2 to 91.5% output of process is increased from 0.023 to 0.41 kg/l x h. EFFECT: increased output of process, increased yield of product.KULIKOV V.M.MASHIN V.N.BOGOLEPOVA E.I.
rhodiumIn the presence of a [Cp*RhCl2](2) catalyst, the Lewis acid In(OTf)(3), and the mild base Na2CO3, aromatic carboxylates and ,-unsaturated ketones undergo a unique hydroarylation/Claisen/retro-Claisen process to give the corresponding indanones. In this carboxylate-directed ortho-C-H...
PREPARATION:A 2-phenoxyethyl halide shown by the formula II (Y is halogen) is reacted with a metahydroxybenzoic acid amide derivative shown by the formula III in the absence of a solvent or in an inert organic solvent such as toluene, xylene, etc. in the presence of a dehydrohalogenating...
Their oxidation with m‐chloroperbenzoic acid (m‐CPBA) was investigated either in the presence or in the absence of Na2CO3. The following conclusions were reached. (1) Oxidation in the presence of Na2CO3affords the corresponding epoxides (4) in moderate to excellent yields. (2) Oxidation in ...
to benzoic acid in the ratio of 1-5 mole to prepare an aqueous benzoate salt; hydrogenating the benzoate salt in an aqueous solution to prepare a cyclohexanecarboxylate salt; and adding an acid aqueous solution to the cyclohexanecarboxylate salt to convert the salt into cyclohexanecarboxylic acid...