Benzene reacts (1) with chlorine, to form (a) substitution products (one-half of the chlorine forms hydrogen chloride) such as chlorobenzene, C6H5Cl; dichlorobenzene, C6H4Cl2(1,4) and (1,2); trichlorobenzene, C6H3Cl3(1,2,4); tetrachlorobenzene (1,2,3,5); and (b) addition produc...
The epoxide (176) reacts with 2-aminopyrimidine in acetonitrile containing HBr to yield an initial enaminoimidazole. The two carbons of the epoxide then act as electrophilic centers allowing cyclization to (177) in 54% yield 〈86T1169〉. Condensation of epoxide (178) with 2-aminopyrimidine gav...
Direct synthesis of a-olefin and benzene in the presence of aluminum trichloride catalyst, alkylation reaction, reactants by alkali washing, water washing, and then by benzene removal, rectification, that is, refined alkylbenzene. chloride method Cl0 ~ C13 n-alkanes are chlorinated to form chl...
(CO)8>-.The benzoyl cluster 7 reacts with EtOTf to yield the nitrene-carbene cluster Fe3(μ3-NPh)2(CO)8(CPh) (9) which has been structurally characterized: Pbca, a=13.668(6) Angstroem, b=17.588(7) Angstroem, c=25.644(8) Angstroem, V=6164(7) Angstroem3, Z=8, R=0.060, Rw...
to the acid chloride which possesses general system VI, the chemical compound which possesses general formula (vi) equimolar or under existing of t- butyl amine and the acid binder which are used at a little excessive quantity, being aprotic solvent concavity warm, it features that it reacts....
and then reacts with aniline to obtain N-phenylthiazole-4-methylamine oxime, then N-phenylthiazole-4-methylamine oxime reacts with p-trifluoromethyl benzoyl chloride to obtain an amidoxime ester, and finally a visible-light-catalyzed free radical reaction is adopted for cyclization to obtain thiazole...
1.A compound having formula (I):or a pharmaceutically acceptable salt thereof, wherein:R1 and R2 are independently C1-C4linear alkyl, or R1 and R2 are alkyl groups taken together with the N to form a 4 to 8 membered cyclic group;R3 is H, or one or more substituents independently select...
. The nitro group is reduced to an amino group to afford a benzene derivative having amino groups at the 1- and 2-positions. The diamino compound is then reacted with a 1,3-bis(alkoxy-carbonyl)-S-alkylisothiourea to give the corresponding 5(6)-substituted benzimidazole 2-carbamate ...
diaminobenzoic acid can be reacted with a 1,3-bis-(alkoxycarbonyl)-S-alkyl isothiourea or (optionally but presently less preferred) a mono(alkoxycarbonyl)-S-alkyl isothiourea to afford 5(6)-carboxy-2-carbalkoxyaminobenzimidazole which is then reacted with an appropriate amine to afford the de...
0.07 ml of benzoyl chloride is added and the mixture is then stirred for 24 hours at ambient temperature. The reaction mixture is extracted with ethyl acetate and the organic phases are then combined and dried over magnesium sulphate. The residue is chromatographed on silica gel (9/1 heptane/...