Porokeratosis is a disorder of keratinization characterized by one or more atrophic macules or patches surrounded by a distinctive hyperkeratotic ridge-like border called a cornoid lamella (Spencer, 2011; Spencer, 2012). The coronoid lamella is a a thin column of closely stacked, parakeratotic ...
Beginning as small papules slightly lighter than the surrounding skin, they tend to darken and become hyperkeratotic with time. While benign, eyelid margin warts can cause punctate keratitis or even corneal pannus. Observation is often adequate, as these lesions tend to eventually outgrow their ...
The neoplastic elements within the lesion tend to be histologically similar in appearance. In some lesions, the darker elements may only demonstrate increased hyperplasia compared to the background lesion. Clinically, the lesion appears as a hyperpigmented patch with scattered darker flat or raised ...
Shadowing correlated most significantly with histological extent of hyperkeratosis (P < 0·0001). Consequently, this method falsely identified non-keratotic acanthotic BCP (n = 3) as melanoma. Highly significant differences between benign naevi (n = 15) and melanomas (n = 24) were found. ...
275Nevoid hyperkeratosisis a rare benign hyperkeratosis of the nipple276,277histologically characterized by orthokeratotic hyperkeratosis, acanthosis, and papillomatosis with occasional keratotic plugging and mild papillary dermal fibrosis. Microscopic differential diagnoses include seborrheic keratosis and ...
While dyskeratotic cells and mitoses can be seen in papillomas, this needs to be distinguished from high-grade squamous dysplasia and invasive squamous carcinoma. It is acknowledged that this can be difficult in some exophytic cases and with downward/endophytic/inverted growth, atypical...
Nodular hyperkeratotic lesions were found within the forehead and scalp. Additionally, skull abnormalities were found, manifested by asymmetry and facial deformation. The patient underwent numerous surgical procedures (plastic and reconstructive) on the face and body with the aim of removing the bleeding...