Topic: Liposomal formulations of non-steroidal anti-inflammatory drugs (NSAIDs) can be used in all population groups (children, adults, and the elderly) which gives them a wide range of applications. NSAIDs oral administration is associated with severe adverse effects in the gastrointesti...
setting in which the drug is given and wider sociocultural beliefs surrounding the ingestion of medicines can all have a major influence on a drug's efficacy. This article explains the term 'placebo' and explores some of the factors contributing to the placebo effect in relation to oral ...
Bioavailability of these constituents after oral administration is low and ranges from approximately 15% to 20%. Penetration of the blood-brain barrier is similarly low with only about 5% of hypericin likely to reach the brain; hypericin's half-life in the brain appears to be a few weeks.(...
Oral administration of drugs is a two-edged sword – on one hand it is a non-invasive and easy-to-handle administration of drugs, on the other hand macromolecular pharmaceutical compounds cannot easily cross the epithelial barrier to reach systemic circulation or they could be inactivated in the...
ferox Miller; the time of harvest also factors into the composition.Uses and PharmacologyAloe latex has been used internally for centuries as a potent cathartic. The aloinosides exert strong purgative effects by irritating the large intestine. In 2002, the US Food and Drug Administration required...
Oral health is paramount for the overall well-being of companion animals, with periodontal disease (PD) being one of the most prevalent oral inflammatory diseases in dogs. PD is a multifactorial disease, prompted by the formation of a polymicrobial biofilm on the teeth surface, known as dental ...
Decades before the develop- ment of molecular methods would allow the engineering of live-attenuated viral vaccines, an attenuated poliovirus vaccine for oral administration (oral polio vaccine, or OPV) was developed by empirical, sequential pas- sage of virulent viruses in heterologous cell- culture...
Food and Drug Administration.Wrinkle treatments and other anti-aging products. Martini N.Collagen supplements.J Prim Health Care. 2019;11(4):385-386. doi:10.1071/HC15947 Fujimoto W, Fukuda M, Yokooji T, Yamamoto T, Tanaka A, Matsuo H.Anaphylaxis provoked by ingestion of hydrolyzed fish colla...
Avoid use with alcohol, barbiturates, sedatives, and other salicylate-containing products because of potential additive irritant effects, including GI tract and platelet function adverse reactions. Willow bark may also interact with oral anticoagulants such as warfarin....
Oral decoctions of bupleurum, subcutaneous injection of the root extract, and oral saikosaponins have shown antipyretic effects in rats and rabbits.(WHO 1999) Nasal gel and nasal spray made from the essential oil of bupleurum reduced fever in rats and rabbits in a dose-dependent manner.(Cao 200...