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Oestrogen is an important sex hormone present in the female body and is responsible for many female characteristics, meaning that when a change does occur in the presence of this hormone the body will react. Progestogen is another prominent female sex hormone that is affected by menopause, althoug...
Overall, BC treatment targets the inhibition of the mechanisms that regulate oestrogen activity. This can be attained either by antagonists of the oestrogen receptor (ER) or by the inhibition of oestrogen synthesis. In this context, preclinical studies in BC/CC rodent models point to a ...