The relevant research literature supports the belief that the psychosocial impact on a child bone marrow donor will be influenced by the survival of the recipient, the age of the donor, and the donor's participation in the decision to donate. In order to empirically validate the actual ...
Exercise in later life is important for bone health and delays the progression of osteoporotic bone loss. Osteocytes are the major bone cells responsible for transforming mechanical stimuli into cellular signals through their highly specialized lacunocan
Because SAMe is a methyl donor in over 100 methyltransferase reactions, it is postulated that supplementation with SAMe may be effective in patients with atypical methylation processes that occur in CNS disorders such as depression.8 The exact mechanism of action is unclear, but preclinical studies ...
transduced to express adenosine deaminase [ADA]) is the first ex vivo stem cell gene therapy approved by the European Medicines Agency (EMA), indicated as a single treatment for patients with ADA-severe combined immunodeficiency (ADA-SCID) who lack a suitable matched related bone marrow donor. ...
Transplantation of Unrelated Donor Umbilical Cord Blood for Nonmalignant Diseases: a Single Institution's Experience with 45 Patients The potential benefits of unrelated donor bone marrow transplantation are offset by the immunologic complications of graft-versus-host disease (GVHD) and i... TH Jaing,...
BONE MARROW IS A RESERVOIR OF REGENERATIVE CELLS FOR RENAL REPAIR Bone marrow-derived (stem) cells contribute to cell turnover and repair in various tissues, including the kidneys.29,30 For example, differentiation of mouse and rat bone marrow cells into glomerular cell phenotypes was described in...
Stem cell therapy is a unique medical treatment that can use donor (allogeneic) or the body's own cells (autologous) to repair and regenerate damaged tissues. This approach is at the forefront of medical research and holds significant promise for enhancing patient outcomes across a variety of co...
Thalassemia,sickle cell anemia,bone marrow failure, or other causes of severe anemia (usually after a blood transfusion is received) Alcoholic liver disease Kidney failure Taking too many iron supplements The treatment for acquired hemochromatosis is largely the same as for hereditary hemochromatosis.Chel...
a few highly specialized institutions. However, with the latest advances in cryobiology, ovarian tissue cryopreservation is rapidly becoming a more widely offered technique by many medical centers around the world. The indications now extend beyond cancer. Even though the risk of reimplanting pre-...
Multicolor confocal microscopy revealed that MM-associated MØ displayed a predominant M2-like phenotype in the bone marrow of MM patient samples, and a high expression of the pro-M2 cytokine macrophage migration inhibitory factor (MIF). To reprogram the protumoral M2-like MØ present in MM to...