Focusing on adult stem cells, this Review aims at summarizing experimental observations supporting the concept that, in cell-based therapies, stem cells operate not through a unidirectional mechanism (e.g., generating neurons) but rather as cellular mediators of a multitude of biological activities ...
Sep 18, 2024 - This article defines and reviews the potential of stem cell therapy as a promising treatment option for various medical conditions. It also discusses and defines stem cells and their importance in the field of regenerative medicine.
Purpose Aspirating bone marrow from the iliac crest using small volumes of 1-4 ml with a 10-ml syringe has been historically proposed for harvesting adult mesenchymal stem cells and described as a standard technique to avoid blood dilution. The disadvantage of repeated small aspirations is that th...
BiophysicsIn addition to chemical cues, the differentiation of stem cells can be influenced by mechanical forces, such as the stiffness of the underlying substrate, but these effects diminish with age. Barreto et al. compared the differentiation of mesenchymal stromal cells from donors aged 11 toDOI...
Stem Cell Safety Is stem cell therapy safe? No method of providing adult stem cells has received more rigorous clinical safety studies than the technology used by Celltex. Dozens of clinical trials conducted by researchers in more than a dozen nations have demonstrated the safety of using MSCs an...
The beneficial effects of mesenchymal stem cells (MSCs) and electroacupuncture (EA) on neurogenesis and related trophic factors remain unclear. Bone marrow MSCs (mBMSC) were transplanted into the striatum of mice with middle cerebral artery occlusion (MCAO), and EA stimulation was applied at two ...
All parts of B. pilosa (the whole plant, aerial parts [leaves, flowers, seeds, stem], and/or roots] have traditionally been used in folk medicine.(Bartolome 2013, USDA 2016, Yang 2014) Synonyms of B. tripartita include Bidens comosa and Bidens connate....
Current sources of stem cells include embryonic stem cells (ESCs) and adult stem cells (ASCs). However, concerns exist with either source: ESCs, with their... BL Yen,HI Huang,CC Chien,... - 《Stem Cells》 被引量: 850发表: 2010年 Taking stem cells to the clinic: Major challenges Ste...
Most studies using adult stem cells (ASCs) and progenitor cells as potential therapeutics for kidney disorders have been conducted in models of acute kidney injury, where the damage mainly affects the tubulointerstitium. The results are promising, whereas the underlying mechanisms are still being ...
Additional insulin resistance indices that were statistically significantly improved with ginger included fasting insulin level, insulin sensitivity, and homeostasis model assessment (HOMA) (P<0.005).(78) Similarly, 63 adult patients with type 2 diabetes mellitus who completed a 12-week intervention of ...