with a fatal dose for children estimated to be 500mg and for adults 20 to 40mg/kg.73Because of diphenhydramine’s cholinergic effects, cautious use ofphysostigmineas anantidotehas been suggested.73Diphenhydramine rapidly distributes from the plasma to the tissue so thatforced diuresisandhemodialysisar...
Usual Pediatric Dose for Cold Symptoms Prescription formulations:1 month and older:Oral: 12.5 to 25 mg orally 3 to 4 times a day; alternatively, weight-based dosing of 5 mg/kg orally per day OR body surface area dosing of 150 mg/m2 orally per day may be used-Maximum dose: 300 mg/day...