Miczek KA, Yap JJ, Covington HE. Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake. Pharmacol Ther. 2008;120:102–28. PubMed CAS PubMed Central Google Scholar Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. Nat Rev Neurosci...
Depressive disorder is a chronic, recurring, and potentially life-endangering neuropsychiatric disease. According to a report by the World Health Organization, the global population suffering from depression is experiencing a significant annual increase. Despite its prevalence and considerable impact on peop...
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE 3rd, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron. 2009;62(3):335–48. Article CAS PubMed PubMed Central Google Scholar ...
Post-traumatic stress disorder (PTSD) is an incapacitating chronic disorder. With a 3.9% lifetime prevalence rate worldwide and a 6.4–7.8% rate in the USA, PTSD’s health burden is substantial1,2,3,4,5. Based on the World Mental Health Surveys, 69.7% worldwide (82.7% in the USA) ...
In a similar vein, stimulating different neuronal subpopulations or circuits was found to produce distinct, sometimes opposite behavioral responses and/or mediate distinctive behavioral phenotypes (Baratta et al., 2009; Cerniauskas et al., 2019; Covington et al., 2010; Ferenczi et al., 2016; H...
Using digital health tools for the Remote Assessment of Treatment Prognosis in Depression (RAPID): A study protocol for a feasibility study. BMJ Open 2022, 12, e059258. [Google Scholar] [CrossRef] [PubMed] Compton, M.T.; Ku, B.S.; Covington, M.A.; Metzger, C.; Hogoboom, A. ...
However, these studies differ from those employing acute mPFC optogenetic stimulation which found increased active coping and reward seeking (Covington et al., 2010; Fuchikami et al., 2015). These divergent results may arise from differences in technical approaches or the specific cell groups ...
Philibin SD, Vann RE, Varvel SA, Covington HE 3rd, Rosecrans JA, James JR, Robinson SE (2005) Differential behavioral re- sponses to nicotine in Lewis and Fischer-344 rats. Pharmacol Biochem Behav 80:87–92 74. Matsuzawa S, Suzuki T, Misawa M (1998) Conditioned fear stress induces ...
indicates that maternal crack cocaine intake might affect the methylation of child’s oxytocin receptors [45]. Changes in the hypothalamic–pituitary–adrenal (HPA) axis are discussed as another possible mechanism mediating the association between PAE and mental health problems in children [46,47], ...
Lachausse RG, Lachausse RG. My student body: effects of an internet-based prevention program to decrease obesity among college students. J Am Coll Health. 2012;60:324–30. Article Google Scholar LeCheminant JD, Smith JD, Covington NK, Hardin-Renschen T, Heden T, LeCheminant JD, et ...