The ideal vaccine will be one able to trigger the maturation of DCs to a state where they can promote the production of tumor-reactive, CD8+ cytotoxic T cells. It is possible that conditions for immunization will finally be optimized; however, the efficacy of a tumor-specific T cell populati...
These are exciting times for cancer immunotherapy. After many years of disappointing results, the tide has finally changed and immunotherapy has become a clinically validated treatment for many cancers. Immunotherapeutic strategies include cancer vaccines, oncolytic viruses, adoptive transfer of ex vivo act...
The ideal vaccine will be one able to trigger the maturation of DCs to a state where they can promote the production of tumor-reactive, CD8+ cytotoxic T cells. It is possible that conditions for immunization will finally be optimized; however, the efficacy of a tumor-specific T cell populati...