Two of the most well-recognised genetic alterations are mutations in epidermal growth factor receptor (EGFR) and fusions of the echinoderm microtubule-associated protein-like-4 (EML4) to anaplastic lymphoma kinase (ALK) in non-small-cell lung cancers (NSCLC) (Paez et al, 2004; Soda et al, ...
It is now well established that the C1 region contains two cysteine-rich zinc-finger-like sequences probably needed for a strong association of PKC with particular lipid-phase conformational forms of biomembranes(3). Moreover, the presence of at least one cysteine-rich sequence is required for ...
One rule of thumb is if you go wider at the bottom, go tighter or at least more fitted at the top.Well maybe that’s my rulebut it tends to balance out this look which scares many women. It’s a nice break from the skinny leg we’ve been wearing forever. Don’t throw out your...
6) Agreed (and I include mobiles and Skype in ‘phone’). But students already use IM, SMS, etc. What frustrates me is when students submit an article lacking a quote and say “Well, I emailed them but they never replied…” Perhaps this is better phrased as ‘Be persistent’. 7) ...
The initial disease may be characterized by a predominance of one clone that responds well to treatment. Yet another inciting event may allow for a new clone with novel genomic abnormalities to emerge, resulting in disease relapse. Some patients have been shown to have up to seven subclones [...
While improvements in operational medicine, as well as safety measures, have increased the survival of injured patients, the overall number of extremity injuries has risen during the most recent military conflicts [1]. The average time for a burn-injured American service member to reach definitive ...
Promising review: "These were awesome! My entire family suffers from motion sickness, especially carsickness. My little one gets sick in the car on a regular car ride through the city. So I knew that a long road trip was going to be a disaster. I was amazed at how well these bands wo...
Promising review:"These were awesome!My entire family suffers from motion sickness, especially carsickness.My little one gets sick in the car on a regular car ride through the city. So I knew that a long road trip was going to be a disaster.I was amazed at how well these bands worked ...