英文名称:Recombinant Chicken BDNF/NT-3 growth factors receptor (NTRK2)Recombinant Chicken BDNF/NT-3 growth factors receptor (NTRK2) is available 1 time 来自 Mybiosource labs,中文名称:重组鸡BDNF/NT-3生长因子受体(NTRK2)重组鸡BDNF
Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of...
By using a culture methodology that allows evaluation of single neurons, we determined that BDNF and neurotrophin-4 (NT-4), which both bind to the TrkB high-affinity receptor, greatly enhanced neuron survival above control cultures. NT-3, which acts via the TrkC high-affinity receptor, a...
Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors which includes nerve growth factor (NGF), neurotrophin-3 (NT-3) and neurotrophin-4/5 (NT-4/5). All neurotrophins are synthesized as preproneurotrophin pre
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor...
Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of...
receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and to a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located ...
Brain-derived neurotrophic factor (BDNF) belongs to the protein family of neurotrophins, of which other members are the homologs nerve growth factor (NGF), neurotrophin 3 (NT-3), and NT-4 [90,151]. BDNF is the predominant member of the neurotrophin family in the adult brain. Initially, BD...
Yes. There are three other members of the neurotrophin family found in mammals, including nerve growth factor (NGF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4/5). Neurotrophins are similar in structure and sequence and are likely derived from a common ancestral gene. NT-6 and -7 ha...
peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser ...