结论 1.VEGF,b-FGF和NOB1在胃癌组织中表达增加. 2.VEGF,b-FGF和NOB1的阳性表达率与胃癌的分化程度,临床分期,有无淋巴结转移和远处转移相关,提示它们与胃癌的发生发展和浸润转移有关,检测VEGF,b-FGF和NOB1表达可作为判断胃癌生物学行为和预后...
NEW MATERIAL:A human b-FGF acceptor DNA base sequence containing a recombinant DNA, a chromosome DNA or cDNA base sequence which code a polypeptide selected from (a) a polypeptide having an amino acid sequence shown by the formula, (b) a mature polypeptide prepared by removing a signal ...
Fibroblast growth factor-21 (FGF-21) is a metabolic regulator that can influence glucose and lipid control in diabetic rodents and primates. We demonstrate that βKlotho is an integral part of an activated FGF-21-βKlotho-FGF receptor (FGFR) complex thus a critical subunit of the FGF-21 rece...
(ELISA)检测52例儿童急性偏瘫患者(感染23例,颅脑损伤18例,脑血管11例)及50例健康对照者的血清b-FGF水平。结果:疾病组和对 照组血清b-FGF水平差异有统计学意义(P<0.05)。不同病因的急性偏瘫患者组间血清b-FGF水平差异无统计学意义(P>0.05)。结论:儿童 急性偏瘫患者血清b-FGF明显升高,恢复期更为显著,提示...
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Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressiv... et al.Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is ...
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These data suggest that inhibition of FGF receptors by compounds like SSR128129E might be useful as a new therapeutic approach for these vascular pathologies. 展开 关键词: Veins Animals Mice, Inbred C57BL Mice, Knockout Mice Apolipoproteins E Receptors, Fibroblast Growth Factor Male Atherosclerosis ...
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