Faster and deeper response to imatinib-based treatment by 12 months revealed to be associated with improved PFS and overall survival. The critical cutoff level seems to be 1% BCR-ABL IS which has been shown to closely correlate with complete cytogenetic remission. Disclosures: Müller: Novartis: ...
PAX5 Wild-Type without IKZF1 (Ikaros) Deletion Is Associated with Prolonged Disease-Free Survival and Low Rate of Cumulative Incidence of Relapse in Adult BCR-ABL1-Positive Acute Lymphoblastic Leukemia (ALL): On Behalf of GIMEMA AL Working Party....
Importantly, the low-risk subtype was characterized by a significantly improved biochemical recurrence-free survival, underscoring the clinical relevance of the ARG-based prognostic signature. To further improve the prognostic accuracy of the signature, patient age, pathological T s...
Comparison of Kaplan-Meier BCR-free survival curves differentiated via (a) Kattan nomogram, (b) Stephenson nomogram, (c) UCSF-CAPRA, (d) MS-KCC nomogram, and (e) CGA classifiers on an independent 2...
Our findings demonstrated the potential of inclusion of mRNA information for BCR-free survival prediction. A random survival forest pipeline was found to achieve high predictive performance with respect to discrimination, calibration, and net benefit. Two mRNA variables, namely ESM1 and DHAH8, were ...
The probability of BCR-free survival is a widely investigated topic as it plays a role in patient treatment decision making [6,7]. The probability of recurrence can be used to determine if and when adjunctive therapies, such as radiotherapy, hormone therapy, and chemotherapy, should be ...
Parameters influencing BCR free survival after salvage radiotherapy.Ohseong, KwonKi, Bom KimYoung, Ik LeeSeokSoo, ByunJaeSung, KimSang, Eun LeeSung, Kyu Hong
MP11-12 REGIONAL LYMPH NODE METASTASIS ON PSMA PET CORRELATES WITH DECREASED BCR-FREE AND THERAPY-FREE SURVIVAL AFTER RADICAL PROSTATECTOMYdoi:10.1097/JU.0000000000001984.12Wuernschimmel, ChristophAmiel, ThomasHeck, MatthiasHorn, ThomasNguyen, Noemi...
Overall survival (OS) and metastasis-free survival (MFS) in men with biochemically relapsed (BCR) prostate cancer after radical prostatectomy (RP) managed with deferred androgen deprivation treatment (ADT): A combined Johns Hopkins and CPDR study...
Early BCR-ABL1 Reduction Is Predictive of Better Event-free Survival in Patients With Newly Diagnosed Chronic Myeloid Leukemia Treated With Any Tyrosine Kinase Inhibitor.. Carmen Fava,Giovanna Rege-Cambrin,Irene Dogliotti,Enrico Gottardi,Paola Berchialla,Bruno Di Gioacchino,Francesca Crasto,Roberta ...