Bcl-X/L mRNA原位杂交试剂盒原位杂交是在一定生物结构基础之上的核酸杂交。这种结构基础可以是一条染色体;一个细菌;更大结构基础是细胞和组织。基本原理是两条核苷酸单链片段,在适宜的条件下,通过氢键结合,形成DNA-DNA、DNA-RNA或RNA-RNA 双键分子,应用带有标记的(有放射性同位素,如3H、35S、32P、荧光素生物素等...
Bcl-xL,Bcl-x L 1)Bcl-x LBcl-xL 1.Objective To investigate the expressions of Bcl-x L and DNA-PKcs in osteosarcoma and their relationships with clinical outcome.目的 探讨Bcl-xL及DNA-PKcs在ⅡB骨肉瘤中的表达及与预后的关系。 英文短句/例句 1.Effects of RNA interference Bcl-xL gene on ...
Bcl-X(L) is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples C Nicot,R Mahieux,S Takemoto,... - 《Blood》 被引量: 0发表: 0年 Bcl-XL is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples Bcl-X(L) is up-regulated by HTLV-...
Bcl-X/L 1. Methods The expression of BAD and BCL-X/L gene in mice thymocyte apoptosis were induced by various dose of glucocorticoids, and the gene expression were determined by immunohistochemical staining. 目的检测BAD和Bcl-X/L基因在小鼠胸腺细胞凋亡的表达,探讨细胞凋亡调控基因在小鼠胸腺细胞凋亡...
Open AccessArticle by Coralie Boulet 1,†, Ghizal Siddiqui 2, Taylah L. Gaynor 1,‡, Christian Doerig 3, Darren J. Creek 2and Teresa G. Carvalho 1,* 1 Department of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University...
中Bcl X L的水平 可能是预测临床结果 白质在细胞存活中发挥冗余作用。天然产物小白菊内酯中的活性成分的药用植物的小白菊。小白菊内酯属于的家庭称为倍半萜内酯化合物,已被赋予多种生物活性。例如,小白菊内酯是常用的用于治疗偏头痛,小白菊提取物可在柜台购买。白菊含有环氧基和外methylenelactone环。在这些反应...
Bcl-X(L) is generally thought to heterodimerize with Bax to prevent cytochrome c release and yet they remain in different cellular compartments, suggesting that their heterodimerization at the mitochondria is not the primary mechanism of Bcl-X(L)-mediated protection. Using chemical cross-linking ...
目的:检测凋亡相关蛋白Bcl-xL、Bcl-Xs/L以及Bcl-6在骨肉瘤中的表达,并探讨其与骨肉瘤预后的关系。方法:应用免疫组化方法检测Bcl-xL、Bcl-Xs/L以及Bcl-6在41例骨肉瘤组织中的表达,并分析其与无瘤生存率及生存时间的关系。结果:Bcl-xL、Bcl-Xs/L在骨肉瘤组织中表达的阳性率分别为53.7%和75.6%,而Bcl-6为阴...
Comparison of wild-type versus mutant BCL-2, BCL-X L indicates these antiapoptotics sequester BH3 domain-only molecules in stable mitochondrial complexes, preventing the activation of BAX, BAK. Thus, in mammals, BH3 domain-only molecules activate multidomain proapoptotic members to trigger a ...
L Zhang,D Xing,M Chen 摘要: Bcl-2 family proteins are implicated as essential regulators in tumor necrosis factor-α (TNFα)-induced apoptosis. Bim L , a BH3-only member of Bcl-2 family, can directly or indirectly activate the proapoptotic Bax and the subsequent mitochondrial apoptotic ...