QIN Yue, PANG Zongran. Study on loroglossin induced myeloid derived suppressor cells apoptosis via activating the Bcl-2 signaling pathway[J]. Tianjin Journal of Traditional Chinese Medicine, 2019, 36(3): 288-291. 洛罗兰...
Qin, B., Zhou, Z., He, J., Yan, C., Ding, S., 2015. IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway. Sci. Rep. 5, 15701.Qin B,Zhou Z,He J,et al. IL-6 inhibits starvation-induced autophagyvia the STAT3/Bcl-2 signaling pathway[J/OL]. Sci...
and Mc1-1, with specific dimeric complexes acting as molecular switches in the cell death signaling pathway. For instance, Bcl-2 can form dimers with pro-apoptotic Bax. If the quantity of Bax exceeds that of Bcl-2, the number of Bax dimers increases, promoting cell death, while...
[3]Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Mol Cell. 2018 Sep 6;71(5):825-840.e6. doi: 10.1016/j.molcel.2018.07.009IF: 16.0 Q1 . Epub 2018 Aug 9. PMID: 301...
Insulin on hydrogen peroxide-induced oxidative stress involves ros/ca2+ and akt/bcl-2 signaling pathways. Free Radic. Res. 2014, 48, 347-356. [CrossRef]Ramalingam M and Kim SJ. Insulin on hydro- gen peroxide-induced oxidative stress involves ROS/Ca2+ and Akt/Bcl-2 signaling pathways. ...
高糖介导人牙周膜细胞凋亡中bcl-2,bax的作用及机制(英文)High glucose can trigger apoptosis in human periodontal ligament cells, which is a complex process.Bcl - 2 is an anti - apoptotic protein that plays a crucial role in this context.The expression level of Bcl - 2 is often altered in ...
Inhibition of autophagy could promote apoptosis of SCC-25 cells which were induced by DHM, increase apoptosis markers CL-PARP and Bax, and decrease Bcl-2 (P<0.05). Conclusions:DHM can induce apoptosis and increase autophagy of HNSCC cells. The mechanism is related to STAT3 signaling pathway. ...
自1985年科研人员首次发现了B细胞淋巴瘤/白血病-2(B-cell lymphoma-2,Bcl-2)基因以来,又陆续发现了其他与Bcl-2高度同源的分子,这些分子都归为Bcl-2家族,其作为抗肿瘤药物靶点,现已被美国药物管理局批准用于癌症治疗。[1] 作为细胞凋亡研究中最受重视的癌基因之一,本文就Bcl-2整理了相关研究资料供各位参考。
[14]Yang Y, Wang Y, Che X, et al. Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib-resistant non-small cell lung cancer cells[J]. Oncol Lett, 2021, 22(1): ...
【关键词】 结肠癌;信号转导通路;增殖;凋亡Stat3 Signaling Pathway Regulates the Expression of bcl2 Family Members and Promotes Survival of Human Colon Cancer CellsAbstract:Objective Signal transducer and activator of transcription 3 (Stat3) is activated ...