Janaghard, Mohsen SedaghatSoleimani, ShahrzadMovafagh, AbolfazlMotallebi, MarziehMousavi, Seyede AmenhSaffar Moghadam, Ali AkbarMoghadam, Vahid ErfaniKhosravi, AyoobMirzaei, Hamid RezaReza Mousavi, Seyed AliIraqi Journal of Cancer & Medical Genetics...
Bcl-2Aim: TNM classification, that had been established according to pathologic and anatomic characteristics of the lesion , is the most important factor in decision of adjuvant therapy in colon cancer. Despite curative resection, recurrence can ocur with a rate of 20-30%...
[4] Warren CFA, Wong-Brown MW, Bowden NA. BCL-2 family isoforms in apoptosis and cancer. Cell Death Dis. 2019 Feb 21;10(3):177. doi: 10.1038/s41419-019-1407-6. PMID: 30792387; PMCID: PMC6384907. [5] Tsujimoto Y. Cell death regulation by the Bcl-2 protein family in the mitochon...
The purpose of this study was to determine the expression of bcl-2 gene in primary breast cancer and its correlation with grade, stage and axillary lymph node involvement.Materials and Methods: The study was a cross-sectional one that was performed on 75 patients with breast cancer admitted to...
Prognostic importance of Bcl-2 expression in colon cancer [Kolon kanserinde Bcl-2 ekspresyonunun prognostik önemi] Aim: TNM classification, that had been established according to pathologic and anatomic characteristics of the lesion , is the most important factor in dec... ASA Alikanoǧlu,...
It follows that therapies designed to counter these alterations might be effective as anti-cancer strategies. Over the past 30 years, research on the BCL-2-regulated apoptotic pathway has led to the development of small-molecule compounds, known as 'BH3-mimetics', that bind to pro-survival ...
Is there potential to target BCL-2 family member isoforms that are expressed higher in cancer? Introduction The BCl-2 family has long been identified for its role in apoptosis. Following the initial discovery of BCL-2 in the context of B-cell lymphoma in the 1980s, a number of homologous ...
Bcl-2 expression and prognosis in childhood acute leukemia. Children's Cancer and Leukemia Study Group. Pediatr Hematol Oncol - Tsurusawa, Saeki, et al.TsurusawaM,Saekik,Katano N,et al.Bcl-2expression and prognosis in childhood acute leukemia.Children’s cancer and leukemia study group. ...
Chromosome abnormalities in poorly differentiated lymphocytic lymphoma. Cancer Res,1979;39:31192,Craig RW. The bcl-2gene family. Semin Cancer Biol,1995;6:353,Baer R. bcl-2 breathes li 15、fe into embryogenesis. Am J Pathol,1994;145:74,Pezzella F, Gatter K. What is the value of bcl-2 ...
Despite progress in treatment of small cell lung cancer (SCLC), its multidrug chemoresistance and poor prognosis still remain. Recently, we globally assessed long non-coding RNAs (lncRNAs) for contributions to SCLC chemoresistance using microarray data,