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Full size image Activation of ZEB1 and tumor migration is dependent on the expression of 4-1BBL and presence of NK cells Single-cell transcriptomic analysis was recently used to study tumor heterogeneity and to identify putative immune checkpoint targets of UM [26]. Using this publicly available ...
Structure of 4-1BBL.aSurface representation of assembled trimer seen from the side. A 90° rotation shows the threefold axis down the center of the trimer.bSuperposition of all three ligand protomers in the asymmetric unit. Individual strands identified by black letters. Variability between protom...
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