Basic Physical Principles of PET-CT The first prototype of a hybrid PET-CT system consisted of a PET scanner connected to a CT scanner and was used in the examination of cancer patients (Beyer et al. 2000). Since both subsystems were already well advanced by that time, integrating the two...
The application of these batch preparation methods for clinically approved formulations has been, however, limited and problematic due the difficulty of generating GMP-compliant aseptic manufacturing methods. In 2011, for example, the European Medicines Agency (EMA) and the Food and Drug Administration ...