Answer and Explanation:1 The process of DNA repair begins with detection of an error in the DNA strand. When new strands of DNA are synthesized, the strand is proofread to... Learn more about this topic: DNA Mi
of CHD6 is required for PARPi resistance, we used virus-like particles and CRISPR-mediated base editing to mutate K492 in the active site of the CHD6 ATPase domain, a mutation known to ablate catalytic activity and that fails to complement loss of CHD6 in functional assays8. We achieved ...
Two miRNAs – miR-128 and miR-342-3p have been both reported by 2 different studies to be useful in the differentiation of glioblastoma from healthy controls. Mir-128 has been reported to be upregulated in one study, while being downregulated in the other, a possible explanation for this fa...
PCSK9 consists of three domains: the N-terminal prodomain followed by the catalytic domain and the C-terminal domain. The catalytic domain mediates the direct interaction with the epidermal growth factor (EGF) A domain of the LDLR as demonstrated by various biochemical methods including crystallograp...
Basic immunology studies the functioning and processes of the defense system of all organisms.Answer and Explanation: In the 18th century, people were affected by the plague. This turned out to be the proof of some type of internal defense system generated by the body......
Although studies have indicated the presence of crotonylation in inflammation, no research has provided a specific mechanistic explanation to elucidate the connection between the two. 4. Physiological processes related to crotonylation In addition to the research on crotonylated diseases, multiple studies ...
Dubex says Microsoft “escalated” their issue on Feb. 8, but never confirmed the zero-day with Dubex prior to the emergency patch plea on Mar. 2. “We never got a ‘real’ confirmation of the zero-day before the patch was released,” said Dubex’sChief Technology Officer Jacob Herbst...
increased LDLR expression and reduced LDL-C [148]. Similarly, genome editing, using a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated system, effectively down-regulates hepatic expression of PCSK9 with the subsequent expected up-regulation of LDLR and reduction in ...
Answer and Explanation: The plasmid vector can carry genetic information to other cells where the foreign DNA is replicated inside the host cell. The four main types of...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts ...
Answer and Explanation: Herpes simplex represents a viral infection that is caused by the Herpes simplex virus. The HSV infections can be classified on the basis of the body...Become a member and unlock all Study Answers Start today. Try it now Create...