D. Technicians can usually perform the calculation of doses using the principles of ratio and proportion. Example: The dose of a drug is 10 mg per kg of body weight. How much would you give a 220-lb. man?a. Step 1: 2.2 lb./1 kg = 220 lb./x ...
to constant weight:it loses not more than 5.0%of its weight. Residue on ignitioná281ñ—Ignite 1g with 0.5mLof sulfuric acid:the weight of the residue is not more than 0.3%. Alcohol-insoluble substances—Boil 1g,accurately weighed,with 50mLof alcohol under a reflux condenser for 15minutes...
Gani R, Hughes H, Fleming DM, Griffin T, Medlock J and Leach S (2005) Potential impact of antiviral drug use during influenza pandemic. Emerg. Infect. Dis.11:1355–1362. Google Scholar Hadeler KP and Castillo-Chavez C (1995) A core group model for disease transmission. Math Biosc. ...
Molecular Formula:C11H14N4O2 Compound Is Canonicalized:True XLogP3-AA:234.11167570 Monoisotopic Mass:234.11167570 Complexity:254 Rotatable Bond Count:3 Hydrogen Bond Donor Count:0 Hydrogen Bond Acceptor Count:5 Topological Polar Surface Area:62.1 Heavy Atom Count::17 Defined Atom Stereocenter Count:0 ...
ED50LD50Application software for economical and convenient calculation of median effective doses, confidence limits, potency ratios and slopes of quantal dose-... GM Schoofs,CC Willhite - 《Journal of Applied Toxicology》 被引量: 19发表: 2010年 Derivatives of glutamic and aspartic acids, a metho...
Firstly, by using a number of drugs with different toxicities, increased anti-tumor effects can be obtained with limitation of the severity of individual drug toxici- ties. Secondly, as the different drugs used in combi- nation chemotherapy have different mechanisms of action, the risk of drug ...
KRANZ H,WAGNER T.Effects of formulation and process vari-ables on the release of a weakly basic drug from single unit ex-tended release formulations.European Journal of Pharmaceutics and Biopharmaceutics. 2006Kranz H and Wagner T (2006). Effects of formulation and process variables on the release...
For the dietary calculation of a food plan, it is essential to determine the nutritional needs (or energy needs) of the person. Energy needs are defined as the dietary energy intake through food sources of carbohydrates, proteins, and fats, which is necessary to maintain energy balance in heal...
Modeling, Simulation, and Model-Based Drug Development—Part 2: Introduction to Pharmacokinetic Modeling Methods DR Mould1 and RN Upton1,2 Population pharmacokinetic models are used to describe the time course of drug exposure in patients and to investigate sources of variability in patient exposure....
Methylene blue (Basic Blue 9) 是一种鸟苷酸环化酶 (sGC),单胺氧化酶 A (MAO-A)和 NO 合酶 (NOS) 抑制剂。Methylene blue 是一种血管加压剂,在医疗中通常用作染料。Methylene blue 具有抗伤害感受,抗疟疾,抗抑郁和抗焦虑作用,可用于高铁血红蛋白血症,神经退行性疾病和异环磷酰胺引起的脑病的研究。 Methy...