Conceptual knowledge can be described as abstract and general knowledge of a domain’s main concepts and their connections (Carey, 2000; Schneider and Stern, 2010a). There is no unified definition of the single concepts that constitute conceptual knowledge (e.g., von Aufschnaiter and Rogge, 20...
Recent advances in genome-wide technology have revealed that the involvement of these dysregulated epigenetic components appears to be extensive. Moreover, there is a growing connection between epigenetic abnormalities in cancer and concepts concerning stem-like cell subpopulations as a driving force for ...
Methods This article describes concepts, methods and procedures to assist in the design of animal and tissue/cell based studies of sex differences in cardiovascular structure, function and models of disease. Results To address knowledge gaps, study designs must incorporate appropriate experimental ...
In the current article, we discuss new developments in the field of CSC research and whether these new concepts can be exploited in clinical practice in the future. Keywords: Cancer stem cells, Targeted therapy, Drug resistance Introduction The principle concept of cancer stem cells (CSC) has ...
Utilizing these new opportunities, geomorphologists have analyzed numerous existing concepts and introduced new ones as well. Allometry, as a concept derived from biology, is a method to describe interrelations between variables. In biology, allometry is defined as the study of the rate of relative...
In the past 15 years, several of the driver kinases have been identified as major targets of therapy. The highlighting example is CML where BCR/ABL-targeting tyrosine kinase inhibitors (TKI) induce major and long-lasting responses [203]. Other similar treatment concepts are emerging in other typ...
The mammary gland in mammalian evolution: A brief commentary on some of the concepts. J. Mammary Gland Biol. Neoplasia 2002, 7, 347. [Google Scholar] [CrossRef] [PubMed] Muschler, J.; Streuli, C.H. Cell-matrix interactions in mammary gland development and breast cancer. Cold Spring ...
In this paper, the author establishes some basic fundamental formulas for the Wiener transform via some concepts and motivations introduced by Segal and used by Hayker et al. We then state the usefulness of basic fundamental formulas as some applications. Keywords: Hilbert space; convolution product...