Quantum-Chemical Study of the Structure and Properties of Hypothetical Superhard Materials Based on the Cubic Silicon−Carbon Nitrides 来自 ACS 喜欢 0 阅读量: 89 作者:R. N. Musin,D. G. Musaev,M. C. Lin 摘要: Density functional B3LYP/6-31G(d,p) calculations have been carried out to ...
Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on knowledge of the drug’s three-dimensional structure and how its shape and charge cause it to interact wi...
"A 100 percent treehouse would take years to create," Joachim said.Depending onthe climate, a house could take anywhere from 5 to 30 years to grow. Fortunately, there's a way to speed up the process. Joachim suggests including ecological materials such as sod (草皮), grasses and living ...
It is to address this gap that we offer the current communication, addressing the following issues: 1. We present the requirements for structure-based chemical classification based on the results of an analysis of the structure-based classes included in the ChEBI chemical ontology; 2. We map...
The LFER model is based on the solvation equation, which contains five main descriptors predicted from chemical structure: solute excess molar refractivity, dipolarity/polarisability, summation hydrogen bond acidity and basicity, and the McGowan characteristic volume. Descriptor values, available for ...
Based on the “on-off-on” fluorescence quenching mode, a novel method was established for determination of both Fe3+ and ascorbic acid. The synthesized NS-CDs can be employed as fluorescence chemical sensors for the direct determination of free iron in the aqueous phase and indirect ...
In this study, considering protein structure, we propose an IDC strategy for protein miniaturization based on the nucleoprotein interaction, dynamic conformation reorganization, and orthologs conservation. We apply the IDC strategy to generate five miniaturized variants of the Cas13 protein and verify that...
Herein, we report the synthesis, a detailed photophysical study and discuss the structure-spectroscopical relationship of this probe family. The utility of the thoughtfully selected probes is demonstrated by 2PM experiments on biological samples. 2. Experimental 2.1. Materials Reagents, solvents and ...
摘要: This paper introduced mobile database and Agent technology,analyzed the the structure of mobile database based on Agent and the insufficiency of existing system.It is expected to provide a basis for future research.关键词:mobile database mobile computing Agent ...
Intensiometric genetically encoded biosensors, based on allosteric modulation of the fluorescence of a single fluorescent protein, are powerful tools for enabling imaging of neural activities and other cellular biochemical events. The archetypical exampl