Base-promoted reaction of phenyl salicylates with aliphatic aldehydes provides the corresponding acetals. Neither methyl salicylate nor aromatic aldehydes participate in this reaction.doi:10.1016/0040-4039(96)00639-9Patrick PerlmutterEvaloni Puniani
Base-catalyzed dehydrohalogenation with potassium t-butoxide in t-butyl alcohol of the acetals obtained from homologues of α-bromoacetaldehyde and ethylene glycol[2-(α-bromoalkyl)-1,3-dioxo-lanes] or 1,3-propanediol[2-(α-bromoalkyl)-1,3-dioxane] provides the corresponding ketene acetal, ...
In the bulk reaction, only small batches can be handled safely because of the almost explosive violence of the reaction once it has been catalyzed by a small amount of peroxide. Probably the most common method of preparation is in solution. In this process, a mixture of 60 volumes vinyl ...
Structure and mechanism in complex general acid-base catalyzed reactions The mechanisms of acid and base catalyzed carbonyl and acyl group reactions are determined largely by the lifetime of the initial addition intermeidate. Catalysis through diffusion-controlled trapping by relatively strong acids or ...
ACETAL(105-57-7) can react vigorously with oxidizing agents. Stable in base but readily decomposed by dilute acids. Forms heat-sensitive explosive peroxides on contact with air. Old samples have been known to explode when heated due to peroxide formation [Sax, 9th ed., 1996, p. 5]. ...
We investigated the reaction between C-alkynylN-Boc-N,O-acetal1aand prochiral nucleophile11ain the presence of Takemoto’s catalystD. Indeed, our strategy enabled the formation ofsyn-propargylamine12a. However, thesyn/antiratio was quite low (2.4:1 dr;Fig. 6a). After considerable experiments,...
The first step is catalyzed by the phenylacetaldehyde synthase (PAAS), converting phenylalanine to phenylacetaldehyde [55]. Phenyacetaldehyde reductase (PAR) catalyzes the second step, reducing the phenylacetaldehyde to 2-phenylethyl alcohol [56]. In silico data showed that RcPAAS was expressed at low...
Catalytic, Enantioselective c:-Additions of Isocyanides: Lewis Base Catalyzed Passerini-Type Reactions[ J]. J Org Chem,2005 ,70( 24 ) :9667-9676.Catalytic, Enantioselective α-Additions of Isocyanides:? Lewis Base Catalyzed Passerini-Type Reactions. Scott E. Denmark,Yu Fan. Journal of Organic...
More recently, the BKM-react database is a non-redundant biochemical reaction database contain- ing known enzyme-catalyzed reactions compiled from BRENDA, KEGG, and MetaCyc [18]. The BKM-react database currently contains 20,358 reactions. Addition- ally, the contents of five frequently used ...
Example 1—Acid Catalyzed Synthesis of Product I Containing Compound-I Corresponding in Structure to Formula (F-I)Anisole was alkylated with a C20 uPAO dimer by acid catalyst as shown below in Scheme 1 to form Product I containing Compound-I....