GLITTER 1is an open-label, randomized, multicenter, Phase III study enrolled 576 subjects with T1DM (HbA1c ≤11.0%) who had been on an approved basal and bolus insulin regimen for at least 6 months prior to screening. Eligible subjects were randomized 1:1 to receive either GL Glargine Injec...
Insulin: basal-bolus more cost effective than premixed for T2DM.The article deals with research which contends that basal bolus insulin is more cost effective than premixed insulin for the treatment of type 2 diabetes mellitus (T2DM).EBSCO_AspPharmacoeconomics & Outcomes News...
Basal/Bolus Insulin Therapy: A Need for Two Daily NPH DosesIGOR BJELINSKIIVANA PAVLICRENARDIJANA BJELINSKIZELJKO METELKO
Basal bolus insulin dosing (BBD) may be defined as the physiological replacement of basal and bolus insulin to achieve near normal glycemia without hypoglycemia and loss of life quality. Normally, continuous and variable basal insulin release provides partial suppression of hepatic glucose production to...
BACKGROUND: Basal and bolus insulin determination in intensive insulin therapy for type 1 diabetes mellitus (T1DM) are currently considered independently of each other. A new strategy that coordinates basal and bolus insulin infusion to cope with postprandial glycemia in pump therapy is proposed. Supe...
basal-bolus insulin therapy An insulin regimen for diabetic patients in which patients use short- or rapid-acting insulins before each meal (bolus doses) and a long-acting insulin once a day (basal dose). Patient care A typical regimen uses approximately equal doses of long-acting insulin ...
A basal insulin dose is calculated using a model predictive control algorithm and physiological data of the subject including desired glucose levels, amounts of the delivered insulin and the measured glucose levels. A manual bolus insulin dose is initiated by the subject. The manual bolus insulin ...
Aim This study compares the effects of two different insulin regimens—basal versus bolus insulin—on metabolic and cardiovascular autonomic function in Japanese participants with type 2 diabetes. Methods Participants were randomly assigned to groups for therapy with insulin glulisine (IGlu) or insulin ...
Five Saudi children with type 1 diabetes mellitus were selected and started on determir-based basal-bolus insulin therapy. Selection criteria included diabetic children with poor diabetic control and recurrent daytime and nocturnal hypoglycemic episodes. The patients were on conventional insulin therapy tha...
Metabolic control of insulin detemir in basal-bolus therapy: treat-to-target study in children and adolescents with type 1 diabetes(†). 来自 ResearchGate 喜欢 0 阅读量: 13 摘要: OBJECTIVE: To assess the efficacy and safety of insulin detemir administered once vs. twice daily in children...