We present a case of a 35-year-old woman presented with a melanocytic lesion microscopically composed of 3 distinct melanocytic populations, suggesting a stepwise progression model to melanoma from a conventional nevus through a melanocytoma stage. This progression was also supported from a molecular ...
DP13 First case of distant metastases from a BAP1-inactivated melanocytoma with melanoma transformation A 43-year-old man presented with a long-standing back lesion causing irritation and bleeding. A presumed pedunculated seborrhoeic keratosis was shave excis... G Jonathan,M Bipin,M Will,... ...
A presumed pedunculated seborrhoeic keratosis was shave excised by his general practitioner; however, histology revealed a BRCA1-associated protein (BAP1)-inactivated melanocytoma (BIM) with melanoma transformation. Histologically, BIMs are identified by the presence of a dermally located expansile ...
The primary melanoma diagnosis was changed to a low-risk BAP1 melanocytoma, based on histological and immunohistochemical findings. Two other low-risk melanocytomas were also excised. The patient was referred to the sarcoma multidisciplinary team, for wide local excision of the MPNST, staging ...