Objectives To evaluate and confirm the histological inflammatory changes that occur in bone and in the overlying mucosa in experimentally induced chronic r... Ayesha,N.,Khalid,... - 《Laryngoscope》 被引量: 233发表: 2002年 Chronic bacterial rhinosinusitis: description of a mouse model. To survey...
Leishmaniasis, the subsequent degree of infection is determined by the cell-mediated response of the infected person. Demonstration of the parasite in peripheral blood smears, ascitic fluid, or biopsy of the bone marrow, spleen, or liver establishes the diagnosis. Sodium stibogluconate, amphotericin...
1 The incidence of periprosthetic joint infection (PJI) is approximately 2%–3%.2 To date, the most common pathogens for prosthetic infection are bacteria, especially Streptococci and Staphylococci, while fungal infection is rare,3 particularly Candida albicans. So far, we know little about the ...
Iron is an essential nutrient for the growth, survival and virulence of almost all bacteria. To access iron, many bacteria produce siderophores, molecules with a high affinity for iron. Research has highlighted substantial diversity in the chemical structure of siderophores produced by bacteria, as ...
Recent studies indicate that bacterial contamination in open wounds may adversely affect the formation of bone and newly formed connective tissue. Certainly, less bacterial burden in wound site improves clinical outcomes in regenerative therapy. A variety of polysaccharides, such as chitosan, and their ...
Colonization of bacteria around native host cells or polymeric implant surfaces results in a dense growth on the surface, which leads to infection. The change of a bacterium from a motile planktonic to a nonmotile long chain of growing cells is a complex, regulated process that depends on sever...
Infectious processes located outside the dura mater (e.g., subgaleal abscess, osteomyelitis, epidural abscess) generally are less severe, but can become chronic and require removal of the involved bone for cure (as in osteomyelitis). When the dural barrier is ruptured, the severity of ...
Although the condition is self-limiting, it can impact the delivery of optimal cancer treatment, since it is associated with clinically significant pain, compromised nutrition, prolonged hospitalization, bloodstream infections and antineoplastic dose reductions [3, 4]. Different approaches to prevent or ...
Bacterial biofilms are a group or cluster of bacteria that are attached to natural or synthetic surfaces and grow embedded in a self-produced polymeric matrix that is composed mainly of exopolysaccharides (EPSs), proteins, and eDNA. From: Bioengineered Nanomaterials for Wound Healing and Infection ...
21 Therefore, relying on conventional antibiotics or bactericidal biomaterials alone is no longer sufficient to treat multidrug-resistant bacterial infections. Therapy with a direct antimicrobial and synergistic effect on immune cells is required. Over the past decade, the use of immunomodulatory agents ...