The lung is a point of intimate contact of the host with its environment and as such is a key point of interaction between animals and microbes. A range of host defence mechanisms exists to protect the lung from infection. These defence mechanisms include physical defences such as the ...
People who have a weakened immune system also have an increased risk for bacterial pneumonia. These include those who recently had anorgan transplant. People who areHIVpositive, or who haveleukemia,lymphoma, or severekidney diseasealso stand a greater chance of developing the infection. Symptoms The...
Although 4T1 mammary carcinoma cell line is a highly tumorigenic and invasive cell line and can spontaneously metastasize from the mammary gland to the lung, our results indicated that chronic bacterial infection accelerated this process. To confirm whether the alteration of the premetastatic niche cau...
Bacterial infection refers to the invasion of a host's tissue by a pathogenic bacteria. Featured COQ6 defies immune and metabolic expectations A COQ6 variant increases susceptibility to pneumococcal infection via non-bone marrow-derived cells without affecting ubiquinone synthesis, challenging traditional ...
The impact of acute lung infection on airway microbiome and host responses We found no significant difference in the bacterial community composition between those with and without pneumonia (PERMANOVA = 0.30) probably because the bronchoscopic samples were obtained from the lung contralateral to the...
aeruginosa, a gram negative bacterial opportunistic pathogen that causes serious lung infections in people with cystic fibrosis, and several TM proteins involved in infection were found to be expressed at sufficient levels for further study. The use of other expression strategies or host species might...
Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection. Article 作者:Cotroneo, Nicole;Hamed, Kamal A;Critchley, Ian A;Stokes, Suzanne S;Pucci, Michael J;Rubio, Aileen BACKGROUND: Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide, with...
The magnitude of the values were clearly associated with the severity of the infection. Trauma of operation or inflammatory events such as viral infections and rejections did not trigger PCT-production. The release of PCT did not depend on the type of pathogens even though Aspergillum resulted in...
Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study ...
Increased IL-13 drives increased bacterial dissemination and mortality followingAcinetobacter baumanniilung infection of zinc-deficient mice and can be countered by anti-IL-13 antibody therapy. Lauren D. Palmer Kacie A. Traina Eric P. Skaar