BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers. T cell antigen receptor (TCR) signaling drives distinct responses depending on the differentiation state and context of CD8(+) T cells. We hypothesized that access of signal-dependent transcription ...
Hematopoietic stem cell and multipotent progenitor (MPP) commitment can be tuned in response to an infection so that their differentiation is biased toward myeloid cells. Here, we find that Bach2, which inhibits myeloid differentiation in common lymphoid progenitors, represses a cohort of myeloid gene...
Another study revealed that BACH2 inhibits NK maturation and cell function in mice and humans, limiting the cytotoxic response to cancer [99]. BACH2 exerts multifaceted effects in tumor immunosuppression and cancer pathogenesis, influencing diverse aspects of immune cell function and tumor biology. ...
SCHENCK RTNC3 100t 2.85mV/V Vmin=Emax/20000 load cell 附延长线15米,可称重100T 称重 MTS LHMD600M1055IA0 传感器 VEM IE2-WE1R 225S 4 TPM HW 电机 TR LP-38 ART.NR:307-00532 线性传感器 MICROSONIC CRM+35/D/TC/E 超声波传感器 connect tech BlueStorm/LP 4 ports RS-232 备件 ...