although the underlying mechanisms are likely different. Nematodes prefer to feed onEscherichia coliOP50 but avoid plant pathogenic bacteria such asR. solanacearum,Pseudomonas syringae, andPectobacterium carotovorumin a binary choice assay. These results suggest significant toxic effects of plant pathogenic ...
Color coding for different strains and conditions according to the legend. The zoomed in data in circle shows the distribution of the GO terms no longer quantifiable in mutant samples. n = 3 independent biological replicates. (J) Absolute quantification of ClpC1 and ClpC2 levels. ClpC2 ...
We have shorter dated debt. We've taken our long-term debt footprint down as we've continued to build the strength of the company. So, there's a lot of different ways. It doesn't have to be securities reinvestment. It can be paying down higher cost liabilities as well. So, we've ...
Compared with small plasmid-based transgenes, BACs are generally more resistant to positional effects, presumably because of their larger size. BAC transgenic mice have uniquely advanced the analysis of distant cis- regulatory elements, rescue of mutant phenotypes and study of human disease-related ...
which was increased in infected mice, can have epithelium remodeling properties74.Akkermansiahas emerged as a genus of major interest, but its contributions to health or disease are still under research: beneficial health effects53,75, as well as detrimental associations, have been reported76,77,78...
GoldenBac allows for generation of multiple constructs in parallel for screening of co-expression conditions To further test the applicability of GoldenBac, we used the method to screen different co-expression constructs coding for multiple chaperones for their ability to increase the solubility of hard...
To examine whether intensive dental prophylaxis can restore oral health, reduce the prevalence of bacteremia and degree of systemic inflammation indicated by CRP levels, we conducted this pilot study examining 30 CKD patients aged 6–26 years, 15 receiving intensive prophylaxis (IP), 15 receiving tr...
A reliable prediction model to distinguish G-from G+bacteremia based on age and plasma IL-6 could facilitate more rapid diagnosis and initiation of rational treatment, possibly because elderly patients suffer from multiple primary diseases and low immune function, conditions that increase susceptibility...
EGF-CAR consistently displayed superior antitumor effects compared to TGFα-CAR and CD19-CAR both in vitro and in vivo. Using a murine xenograft NSCLC model, PVAQ.EGF-CAR provided a significant survival benefit without apparent toxicity; this lack of toxicity was also seen in the NHP model, ...
CYP3A4 overexpression had no negative effects on cell proliferation, barrier function, and P-glycoprotein activity in Caco-2 cells. Thus, we succeeded in establishing Caco-2 cells with CYP3A4 metabolizing activity comparable to in vivo human intestinal tissue. This cell line would be useful in ...