β2-microglobulin fusion proteins and modified forms of β2-microglobulin are disclosed. The fusion proteins are shown to incorporate onto the surface of MHC I expressing mammalian cells and to cause an increased cytotoxic T-cell response to antigens presented by such cells. The fusion proteins ...
Multivariate analysis showed that β2 microglobulin (β2-M) ≥4.0 mg/L (P = 0.020), rash/pruritus (P = 0.004), performance status (PS) ≥2 (P = 0.006), age >60 years (P = 0.006) and extranodal sites (ENSs) >1 (P = 0.029) were independent risk ...
B265 The mTOR Pathway is Activated in a Subset of MM and Correlates with High B2-microglobulinPlasma cell leukemia (PCL) is a rare and aggressive plasma cell disorder, characterized by the presence of a peripheral blood absolute plasma cell count of at least 2 x 109/l and more than 20% ...
β2-microglobulin is a human serum protein of low molecular weight and unknown function (1). Normally present in serum in low concentrations (2 g/ml), it is degraded by the kidney (2). In the presence of renal failure serum concentrations as high as 70 g/ml may occur (3, 4). Patie...
Only Ct values < 35 were included in the calculations, and gene expression was related to the mean expression of β2 microglobulin (β2M) and GAPDH as housekeeping genes, since these were the two most stable of the five housekeeping genes included in the array, and the transcripts of ...
368A NEPHROLOGY e1630 TUBULOINTERSTITIAL INVOLVEMENT IN ULAR DISEASE - DIAGNOS I S USING B2 MICROGLOBULIN. Ronald J . Portma n, Anne Richardson, and Alan M.Robson , Wash ington University Schoo l of Medicine, St. Louis Children ' s Hospital, Departmen t of Ped iatrics, St. Louis, MO ...
β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (so not red blood cells). In humans, the β2 microglobulin protein is encoded by the B2M gene. β2 microglobulin lies lateral to the α3 chain on the cell surface. ...
Beta-2-Microglobulin (B2M) ELISA Kit β-2-微球蛋白(B2M)ELISA试剂盒 crystalchem 80955 High Sensitivity C-Reactive Protein (hs-CRP) ELISA Kit 超敏C反应蛋白(hs-CRP)ELISA试剂盒 crystalchem 80956 Human Cortisol (Serum) ELISA Kit 人类皮质醇(血清)ELISA试剂盒 crystalchem 80957 Hu...
The results of our study showed that the levels of high-sensitivity C-reactive protein (hs-CRP), albumin, prealbumin, and beta-2 microglobulin in the serum of peritoneal dialysis patients with uremia varied significantly during the course of treatment. 3. 结论 3.1 研究意义 尿毒症是一种严重的肾...
描述: HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymp...