The MRD maps to an 8-amino acid (339–346) segment of the C-terminal of native p53. The function of this domain is selective for p53, because it did not affect VP16-mediated activation. Also, mutations of two amino acids, M340P and F341D, were sufficient to prevent p53-mediated ...
An increasing number of studies indicate that adrenergic signalling plays a fundamental role in chronic stress-induced tumour progression and metastasis. However, its function in gastric cancer (GC) and its potential mechanisms remain unknown. The expres
NGINX Agent provides an administrative entry point to remotely manage, configure and collect metrics and events from NGINX instances - agent/go.work.sum at 0e16af7445943e6529b1b2e59aaf5fad639c0333 · nginx/agent
The blood–tumor barrier (BTB) contributes to poor therapeutic efficacy by limiting drug uptake; therefore, elevating BTB permeability is essential for glioma treatment. Here, we prepared astrocyte microvascular endothelial cells (ECs) and glioma microva
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from 44.5 pg ml−1at 6 h after immunization (day 0.3) to 383.1 pg ml−1at 6 h after the secondary immunization (day 21.3; Fig.5a). The data generated with the Luminex assay provided evidence that IFN-γ and other cytokines like IL-2, CCL2, CCL4 and CCL5 were enhance...
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Google Maps is the Most-Used Smartphone App in the WorldStatista
Google Maps是现代人密不可分的一部分。最近,一张Google Maps的街景画面拍下一名谋杀案疑犯将尸体装进车中的画面,最终成为关键线索,令警方成功逮捕涉案的两名疑犯。 ▲Google Maps街景画面捕捉到疑犯藏尸的情况。(Google Street View) ...
Although Eph-ephrin signalling has been implicated in the migration of cranial neural crest (CNC) cells, it is still unclear how ephrinB transduces signals regulating this event. We provide evidence that TBC1d24, a putative Rab35-GTPase activating protei