As a result of screening by using Murine B16F10 melanoma cell line constitutively expressing NF-B luciferase reporter gene, we identified Saikosaponin B2 as an effective inhibitor for etoposide-induced NF-B activation in B16F10NFkB cells. Saikosaponin B2 sensitized etoposide-induced cell death in ...
Finally, intragastric administration of JB suppressed tumor growth and induced tumor apoptosis in mouse xenograft model of murine melanoma B16F10 cells. Taken together, these results suggest that JB could induce apoptosis through the mitochondrial pathway and inhibit tumor growth. The inhibition of ...
We examined the effects of photodynamic hyperthemal therapy (PHT), which is a combination of photodynamic therapy (PDT) and hyperthermia (HT), on the apoptosis and cell cycle progression of murine melanoma B16F10 cells. The percentage of apoptotic cell was determined by flow cytometry using fluor...
Because of the depigmenting effect of α-mg on murine melanoma cells, we also examined the effect of α-mg on normal human epidermal melanocytes (NHEMs) melanogenesis. Initially, the MTT test was conducted to investigate the effect of α-mg on the proliferation of NHEMs (Fig. 5A). We ...
Moreover, some investigators have recently shown that transduction with IL-18 cDNA to tumor cells inhibited their growth in vivo (Tan et al, 1998;Heuer et al, 1999;Tasaki et al, 2000). A murine melanoma cell line B16F10 has many features that may correspond to the poor immunogenicity of ...
Genetically modified murine adipose-derived mesenchymal stem cells producing interleukin-2 favor B16F10 melanoma cell proliferation[J].{H}Immunological Investigations 2015,44(3).Bahrambeigi V, Ahmadi N, Salehi R, Javanmard SH. Genetically modified murine adipose-derived mesenchymal stem cells producing ...
B16F10 murine melanoma cells were treated with jararhagin (jara), a disintegrin-like metalloproteinase isolated from Bothrops jararaca snake venom, and jari (catalytic domain inactivated with 1,10-phenanthroline). Viability and adhesion cells were evaluated by MTT assay. The expression of caspase-3 ...
We have tested this hypothesis by examining agouti inhibition of both melanocortin-stimulated cyclic adenosine monophosphate production and the binding of a radioactive melanocortin analog in the murine B16F10 melanoma cell line. Inhibition of melanocortin-induced cyclic nucleotide accumulation did not ...
Such DNA vaccine was tested against syngeneic B16F10-Nex2 murine melanoma. In vivo experiments showed a protective effect mediated by high production of IFN-γ and down-regulation of anti-inflammatory interleukins mainly by NKT 1.1+ T cells. Biochemoterapy in vivo with plasmid encoding mIL-13R...
Effects of EGb 761 and Korean Red Ginseng on Melanogenesis in B16F10 Melanoma Cells and Protection against UVB Irradiation in Murine Skin;vol. 42008. Google Scholar 19 T.W. Tse Hydroquinone for skin lightening: safety profile, duration of use and when should we stop? J Dermatol Treat, 21 ...