1996. B16F10 murine melanoma cells express interleukin-2 and a functional interleukin-2 receptor. Tumour Biol. 17:155.Garcia de Galdeano A, Boyano MD, Smith-Zubiaga I, Canavate ML. B16F10 murine melanoma cells express interleukin-2 and a func- tional interleukin-2 receptor. Tumour Biol. ...
From these results, we concluded that an IL-2 signalling system is present in murine B16F10 melanoma cells and that IL-2 favors B16F10 cell proliferation, suggesting a role for this cytokine in the tumoral activity of these cells. 展开 关键词: B16F10 melanoma Interleukin-2 receptor Interleukin...
Finally, intragastric administration of JB suppressed tumor growth and induced tumor apoptosis in mouse xenograft model of murine melanoma B16F10 cells. Taken together, these results suggest that JB could induce apoptosis through the mitochondrial pathway and inhibit tumor growth. The inhibition of ...
AIM: To study the expression of murine interleukin-12(mIL-12) gene in B16F10 melanoma cells. METHODS: mIL-12 gene was inserted into pcDNA3.1 eukaryotic expression vector by DNA recombination and then transfected into B16F10 melanoma cells by electroporation. The integration and expression of mIL-...
Melanoma;Macrophage;LPS;Viabilityofphagocytizing;MTF 黑素瘤(melanoma)发病率和死亡率以每年递增 4%～6%,远超过其他恶性肿瘤。其早期易发生淋巴 和血道转移,预后较差,已对人类健康构成极大威 胁_lJ。黑素瘤病因迄今不明,但本病的发生、发展及 转归与机体的免疫系统关系密切。巨噬细胞历来被认 ...
C57Bl/6 mice subjected to PNX were given an intravenous injection of B16F10 melanoma cells at various stages of compensatory lung growth. Animals injected with B16F10 cells during the linear phase of the response had 77% to 260% more pulmonary metastases than mice subjected to thoracotomy ( P...
Murine melanoma B16F10 cells were purchased from ATCC through Sumitt Pharmaceuticals (Tokyo, Japan). Colon tumor Colon-26 (CT26) cells were originally obtained from Dr. K. Nomoto, Kyushu University (Fukuoka, Japan) and maintained in our laboratory. These cells were cultured in D-MEM (high glu...
B16F10 murine melanoma cells were treated with jararhagin (jara), a disintegrin-like metalloproteinase isolated from Bothrops jararaca snake venom, and jari (catalytic domain inactivated with 1,10-phenanthroline). Viability and adhesion cells were evaluated by MTT assay. The expression of caspase-3 ...
We have tested this hypothesis by examining agouti inhibition of both melanocortin-stimulated cyclic adenosine monophosphate production and the binding of a radioactive melanocortin analog in the murine B16F10 melanoma cell line. Inhibition of melanocortin-induced cyclic nucleotide accumulation did not ...
[2]Κim HN,Κim H,Κong JM,et al.Vitamin C down-regulates VEGF production in B16F10 murine melanoma cells via the suppression of p42/44 MAPΚ activation[J].J Cell Biochem,2011,112(3):894-901. [3]Nagengast WB,Hooge MN,van Straten EM,et al.VEGF-SPECT with ¹¹In-bevacizumab ...