目的:研究B16F10黑素瘤细胞培养上清对同基因小鼠脾淋巴细胞的抑制作用.方法:制备 B16F10黑素瘤细胞培养上清,作用于同基因小鼠脾淋巴细胞,通过PHA刺激和混合淋巴细胞反应,用MTT法检测淋巴细胞的增殖活性.结果:在 B16F10黑素瘤细胞培养上清的作用下,PHA诱导的同基因小鼠脾淋巴细胞增殖率平均为63.00%,明显低于对照组,差...
Zhang Y, Liu Z, Hao X, Li A, Zhang J, Carey CD, Falo LD, You Z. Tumor-derived high-mobility group box 1 and thymic stromal lymphopoietin are involved in modulating dendritic cells to activate T regulatory cells in a mouse model. Cancer Immunol Immunother. 2018;67(3):353–66. https...
However, the use of QDs is limited by their toxicity in biological systems, mostly associated with Cd+2 release and reactive oxygen species (ROS) generation. Also, little is known about the effects of QDs on the metastatic capacity of cancer cells. With this in mind, we developed a ...
Moreover, the CD44 expression significantly increased in the colonies compared with the NIH3T3 cells, and the CD133 expression was induced by the B16F10 cell-derived proteins. Interestingly, the NIH3T3 cells did not express Oct4, Sox2, and CD133, but the induced colonies expressed them (Fig....
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Analysis of the melanoma tumor sections on groups (L1 and L2) which received extracts of Bauhinia variegata leaf along with cyclophosphamide at 500 and 750 mg/kg, body weight from the day of tumor induction showed a pro- gressive increase of apoptotic cells and perimeter of blood ab cd ef ...
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These studies have emphasized the usefulness of marine algae as functional cosmetic materials [24]. Leathesia difformis (L.) Areschoug (L. difformis) is a yellowish-brown alga that is found attached to rocks or other plants. Fucoidan from L. difformis has apoptotic [25], antiviral [26], ...
To determine whether both Ox-Hcs promote M1/M2 polarization of macrophages in the tumor tissue, we used FACS to measure the distribution of F4/80+CD86+ (M1) and F4/80+CD206+ (M2) in a single-cell suspension, prepared from a tumor (Figure 4). In the mild therapy groups, significantly...
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