Serum vitamin B12levels of the untreated group during the spring and summer averaged 87 pmolllitre, with the lowest mean monthly level of 73 pmolllitre occurring in November. Mean urinary methyl malonic acid remained low (less than 36 p.molllitre) in both groups. There was no weight gain ...
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“Among patients with cobalamin deficiency, the blood level of methylmalonic acid was about eight times greater than among controls. However, in the cerebrospinal fluid, the level of methylmalonic acid was, on the average, 600 times greater than among control patients.”Ibid. Low B12 and Brain A...
Abacavir Cyanocobalamin may decrease the excretion rate of Abacavir which could result in a higher serum level. Aceclofenac Aceclofenac may decrease the excretion rate of Cyanocobalamin which could result in a higher serum level. Acemetacin Acemetacin may decrease the excretion rate of Cyanocobalamin ...
Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, University of Cambridge, Addenbrooke’s Hospital, Box 289, Cambridge, CB2 0QQ, UK Sarah Finer Nuffield Department of Obstetrics and Gynaecology University of Oxford Level 3, John Radcliffe Hospital, Oxford, ...
Therefore, we also aimed to determine serum normal lower limit of vitamin B12 in this study. Methods: The study group consisted of 215 infants who had been tested for serum B12 level during the first 4 months of life out of 335 cases referred to the centre from June 2011 to June 2016 ...
accumulation of precursor substances, such as homocysteine and methylmalonic acid, disruptting thehomeostasis of vascular and nerve, and at the same time disrupt the DNA methylation reaction, purine pyrimidine and protein synthesis of inner ear cells at the cellular level, leading to cell function ...
Factors determining the level of activity of 3,5,3'-triiodothyronine-responsive hepatic enzymes in the starved rat. The rate of appearance of 2 thyroid hormone-responsive hepatic enzymes, mitochondrial alpha -glycerophosphate dehydrogenase ( alpha -GPD) and cytosolic mal... OPPENHEIMER JACK H.,SCHWAR...
26、CTICE POINTSpA normal serum vitamin B12 level does not accurately reflect the underlying tissue availability of cobalamin and may be falsely reassuring.pIn the presence of a clinical picture suggestive of SCD of the spinal cord, methylmalonic acid or homocysteine levels should be measured to exc...