【翻译】诊断该病种时需排除慢性淋巴细胞白血病(CLL)进展,慢性淋巴细胞白血病伴幼淋巴细胞增多和形态相似于B幼淋巴细胞白血病但具有t(11; 14) (q13;q32) [IGH/CCND1]基因易位或表达SOX11的淋巴组织增生; they instead constitute mantle cell lymphoma with leu...
On adoptive transfer of in vitro expanded B10 cells, collagen-immunized mice showed a marked delay of arthritis onset with reduced severity of both clinical symptoms and joint damage, accompanied by a substantial reduction in the number of Th17 cells. To determine whether B10 cells directly inhibit...
另有研究发现,CD5与CD19共表达的B细胞程序性死亡受体1(PD-1)过表达 [ 9 ],慢性淋巴细胞白血病(CLL)就是以CD5、CD19共表达为特征的恶性B细胞肿瘤,越来越多的证据表明PD-1通路参与CLL的肿瘤逃避 [ 10 ]。在DLBCL中,PD-1表达见于活化B细胞型-DLBCL和EB病毒阳性DLBCL,提示PD-1表达可能是CD5阳性DLBCL未来...
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BTK inhibitors impair humoral and cellular responses to recombinant zoster vaccine in CLL. Blood Adv. 2022;6(6):1732–40. Article CAS PubMed PubMed Central Google Scholar Din MAU, Liaqat H, Anwer F. Vaccine responses in patients with chronic lymphocytic leukemia on treatment with Bruton ...
Acalabrutinib (Calquence) is a targeted cancer treatment used for chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL), in certain patients. It helps slow the progression of cancer and helps extend patients' lives. Acalabrutinib works by blocking ...
淋巴瘤包括但不限于霍奇金淋巴瘤和非霍奇金淋巴瘤,例如B细胞淋巴瘤(例如弥漫性大B细胞淋巴瘤(DLBCL)、滤泡性淋巴瘤(follicular lymphoma)、慢性淋巴细胞白血病(chronic lymphocytic leukemia,CLL)、小淋巴细胞淋巴瘤(small lymphocytic lymphoma,SLL)、套细胞淋巴瘤(mantle cell lymphoma,MCL)、边缘区淋巴瘤(marginal ...
Most patients with CLL have an indolent disease course—up to 70% are asymptomatic with incidental lymphocytosis at diagnosis. In these cases, observation is recommended until the patients meet indications for treatment. Symptomatic patients may present with B symptoms (fever, night sweats, ...
The article describes the case of a 74-year-old woman with leukocytosis with lymphocytosis with any other signs or symptoms where treatment-refractory immune thrombocytopenia (ITP) in chronic lymphocytic leukemia (CLL), during therapy with the Bruton's tyrosine kinase inhibitor acalabrunitib ...
Patients with symptoms of dry mouth and dry throat lasting for more than three months who were positive for anti-SSA/anti-SSB antibodies were clinically diagnosed with pSS and classified into the pSS group. Patients confirmed as DLBCL through cellular immunohistochemistry analysis of tissue pathology ...