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Tevimbra is a monoclonal antibody that belongs to a class of drugs that bind to either the programmed death receptor-1 (PD-1) or PD-ligand 1 (PD-L1), blocking the PD-1/PD-L1 pathway, thereby removing inhibition of the immune response, potentially breaking peripheral tolerance and inducing ...
3.3. Microscope Imaging (SEM, TEM and Confocal) SEM images showed that gelatin nanoparticles, LMW, and HMW chitosan nanoparticles had a filamentous, round, and oval-like morphology, respectively (Figure 2). TEM images of LMW chitosan NPs confirmed their morphology and showed that their nominal ...
Jan, R.; Chaudhry, G.E. Understanding Apoptosis and Apoptotic Pathways Targeted Cancer Therapeutics.Adv. Pharm. Bull.2019,9, 205–218. [Google Scholar] [CrossRef] [Green Version] Elmore, S. Apoptosis: A review of programmed cell death.Toxicol. Pathol.2007,35, 495–516. [Google Scholar] ...
In this regard, a further test was performed using Scanning Electron Microscopy (SEM) with the aim of better-understanding the effects of combined UV radiations on biofilm morphology. In this case, we selected two different bacterial strains: Salmonella enterica 706 RIVM and Staphylococcus aureus AT...
Miyata, Y.; Nakamoto, H.; Neckers, L. The therapeutic target Hsp90 and cancer hallmarks.Curr. Pharm. Des.2013,19, 347–365. [Google Scholar] [CrossRef] Dienstmann, R.; Martinez, P.; Felip, E. Personalizing therapy with targeted agents in non-small cell lung cancer.Oncotarget2011,2, ...
The results presented herein raised the question as to whether the combination of MDL28170 and AmB should be effective against differentLeishmaniaspp. In a previous work from our group [11], we showed that sixLeishmaniaspecies, includingL. amazonensisandL. chagasi, presented susceptibility to MDL...
The results are presented as the mean ± standard error of the mean (SEM) for each repeated experiment. Statistical significance (p< 0.05) was assessed by one-way ANOVA for multiple groups and Student’st-test using the GraphPad Prism 5 software (GraphPad Software Inc., La Jolla, CA, USA...
Cisplatin (CIS) is an effective chemotherapeutic agent against different cancers. The use of CIS is associated with acute lung injury (ALI) and other adverse effects, and oxidative stress and inflammation were implicated in its toxic effects. Candesartan