has shown that there is a considerable variance of the helical structure of DNA, based on the sequence. For example, a 200-bp piece of DNA can run as if it were more than 1000 bp on an acrylamide gel if it has the right sequence. The double helix is not the...
Focuses on structure of a B-form DNA/RNA chimera (dC)(rG)d(ATCG) complexed with daunomycin at 1.5 Å resolution. Interactions between nucleic acids and drug molecules; Method used to study the analysis; Daunomycin binding to DNA/RNA chimera....
Structure of the A-Form and B-Form of DNA from Deuterium NMR Line Shape Simulation 来自 ACS 喜欢 0 阅读量: 33 作者:AA Nevzorov,S Moltke,MF Brown 摘要: Simulation of experimental solid-state deuterium (2H) NMR spectra of nucleic acid fibers allows one to deduce important microscopic ...
Crystal Structure of a B-Form DNA Duplex Containing (l)-α-Threofuranosyl (3‘→2‘) Nucleosides: A Four-Carbon Sugar Is Easily Accommodated into the B... Crystal structure of a B-form DNA duplex containing (L)-R- threofuranosyl (3′ f 2′) nucleosides: A four-carbon sugar is...
Figure 3a shows a schematic drawing of the 20-mer DNA duplex observed in this crystal structure. All the inter-phosphate distances across the minor and major grooves of the DNA duplex are drawn. The oligonucleotides annealed to form a Watson-Crick double stranded DNA with 2 complete helical ...
The structure of DNA is a ___. A. single helix B. double helix C. linear chain D. ring structure 相关知识点: 试题来源: 解析 B。DNA 的结构是双螺旋(double helix)。选项 A 单螺旋不符合实际。选项 C 线性链不准确。选项 D 环状结构也不正确。反馈...
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DNA polymerase ζ (Polζ) belongs to the same B-family as high-fidelity replicative polymerases, yet is specialized for the extension reaction in translesion DNA synthesis (TLS). Despite its importance in TLS, the structure of Polζ is unknown. We present cryo-EM structures of theSaccharomyces...
In the region where thermal fluctuations can be neglected the classical mechanical approach is employed and equations governing the detail structure of the DNA are derived with some analytical results obtained. The transition from theB-form toS-form can be understood in terms of an effective ...