Borrower will (a) comply with the funding requirements of ERISA with respect to the Plans for its employees, or will promptly satisfy any accumulated funding deficiency that arises under Section 302 of ERISA; (b) furnish Lender, promptly after filing the same, with copies of all reports or ...
Differences include plasma cell neoplasms, high-grade B-cell lymphoma (double hit lymphoma), follicular lymphoma, LPD with immune deficiency and dysregulation, extranodal large B-cell lymphoma, transformations of indolent B-cell lymphomas, and diffuse large B-cell lymphoma, not otherwise specified. ...
20,97 However, the use of restriction enzymes may limit the detection of some integration junctions due to the deficiency of the corresponding cutting sites upstream and downstream of the virus-cell DNA junctions. Some uncommon PCR technologies also used to detect HBV DNA integration are ...
fees or other governmental charges of any nature which were required to have been paid have been paid or provided for, and the Company has no knowledge of any actual or threatened assessment of deficiency or additional tax or other governmental charge or a basis for such a claim against the...
Deficiency of only one gene product is reflected by the absence of its corresponding metabolites. Without oxidative deamination of NE by MAO-A in sympathetic nerves, for example, 3,4-dihydroxyphenylglycol will not be formed. Lack of both enzyme subtypes would result in the loss of both 3,4-...
Performance of B-doped SrTiO3/Ni sheet for supercapacitor material application. Key Eng. Mater. 851, 25–31 (2020). 58. pSherafhoarbmuadndciens, uSp. eertcaalp.aPteorlyrya.nCileinraem-S.rITnitO. 435n,a1n1o4c2u8b–e11b4a3s7ed(2b0i1n9a)r.y nanocomposite as highly stable electrode ...
Why would TMEM106B deficiency and overexpression both disrupt lysosome function? A previous hypothesis suggests that TMEM106B level is critical for normal lysosome function and an imbalance towards either direction could disrupt this delicate equilibrium. In a Tmem106b transgenic mouse model, total prot...
Neither the Seller nor the Directors and officers (and employees responsible for Tax matters) of the Company have received, or expect to receive, from any taxing Authority any written notice of a proposed adjustment, deficiency, underpayment of Taxes or any other such notice which has not been ...
The question is whether or not TACI is important for B cell tolerance as a whole. A recent study withcommon variable immune deficiency(CVID) patients carrying a mutation in theTACIgene confirmed that indeed B cell tolerance in these patients is defective[132], confirming in vivo the important ...
In gene therapy, genetic information is delivered to a host cell in order to either correct (supplement) a genetic deficiency in the cell, or to inhibit an unwanted function in the cell, or to eliminate the host cell. Of course, the genetic information can also be intended to provide the...