类风湿关节炎(RA)是一种全身性的自身免疫性关节疾病,其临床特征主要有滑膜炎和关节骨破坏,严重者致残。多种类型的免疫细胞参与RA进展,B细胞是介导体液免疫的核心群体,它在RA中发挥重要作用,近年来越来越受到重视。该文综述目前治疗RA的B细胞相关靶向药物的最新研究进展。 关键词: 类风湿关节炎; B细胞; 靶向治疗 ...
To start with, physical activity increases the efficiency of your heart and lungs.During exercise, your heart and lungs must work harder.This extra effort makes them grow stronger over the long term. 【拓展】 in the short term从短期...
BC is more proactive and generally refers to the processes and procedures an organization must implement to ensure that mission-critical functions can continue during and after a disaster. This area involves more comprehensive planning geared toward long-term challenges to an organization's success....
In other words, having financial intelligence enhances your competence to handle money responsibly and wisely over the long term. It empowers you to make good financial decisions and to take advantage of money-making 2 (opportunity) that present themselves. You can improve your financial IQ by ...
achieve his goals. American capitalism hasflourishedthanks to the predictable application of rules. If,at themargin, that rules-based system issupersededby anad hocapproach in which businessmen musttake heedandpay homage tothewhimof King Donald, t...
D) It enables them to focus on long-term investments. 24. A) They count on others to take the responsibility. B) They change their investment strategy in time. C) They think they themselves are to blame . D) They persist rather than get discouraged. ...
Endovascular treatment of common iliac artery aneurysms using the bell-bottom technique: long-term results. J Endovasc Ther, 2010, 17(4): 504-509. 17 Wang L, Liang S, Xu X, et al. A Comparative Study of the Efficacy by using Different Stent Grafts in Bell-Bottom Technique for the ...
F. et al. Long-term maintenance therapy using rituximab-induced continuous B-cell depletion in patients with ANCA vasculitis. Clin. J. Am. Soc. Nephrol. 9, 736–744 (2014). Article CAS PubMed PubMed Central Google Scholar Cornec, D., Avouac, J., Youinou, P. & Saraux, A. ...
Antoine C, Muller S, Cant A, Cavazzana-Calvo M, Veys P, Vossen J, Fasth A, Heilmann C, Wulffraat N, Seger R, Blanche S, Friedrich W, Abinun M, Davies G, Bredius R, Schulz A, Landais P, Fischer A (2003) Long-term survival and transplantation of haemopoietic stem cells for ...
The heterostructured ZnO-Au@ZIF-7 allows for ppb-level detection of NO2 (Response = 1.7–5 ppb) with excellent repeatability and provides improved selectivity, anti-humidity capacity, and long-term stability compared with bare ZnO, Au-doped ZnO or ZnO@ZIF-7 core-shell nanorod arrays. ...