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目的 系统评价复发或难治性B细胞急性淋巴细胞白血病相关的药物经济学研究,总结其模型结构、参数纳入等方法学部分,为今后复发或难治性B细胞急性淋巴细胞白血病相关干预措施开展药物经济学评价提供参考。方法 计算机检索PubMed、EMbase、The Cochrane Library、CNKI和WanFang Data数据库,搜集关于复发或难治性B细胞急性淋巴细胞...
类风湿关节炎(RA)是一种全身性的自身免疫性关节疾病,其临床特征主要有滑膜炎和关节骨破坏,严重者致残。多种类型的免疫细胞参与RA进展,B细胞是介导体液免疫的核心群体,它在RA中发挥重要作用,近年来越来越受到重视。该文综述目前治疗RA的B细胞相关靶向药物的最新研究进展。 关键词: 类风湿关节炎; B细胞; 靶向治疗 ...
Haddad E, Landais P, Friedrich W, Gerritsen B, Cavazzana-Calvo M, Morgan G, Bertrand Y, Fasth A, Porta F, Cant A, Espanol T, Muller S, Veys P, Vossen J, Fischer A (1998) Long-term immune reconstitution and outcome after HLA-nonidentical T cell-depleted bone marrow transplantation ...
The result of these qualitatively different B-cell responses is a division of labor. (i) Extrafollicular B-cell responses generate an early antibody response within a few days without time-consuming SHM and without inducing immunological memory in terms of long-term antibody production or MBCs. (...
No matter how much data a city has,addressing urban challenges will still require stable long-term(8)___,good management and effective personnel.If smart data identifies a road that needs paving,it still needs people to show up with tools. As ...
5C). Additionally, TRPV1 was found in the unseeded RCN network, which is activated by inflammatory molecules and involved in calcium homeostasis [47] and also mediates synaptic long-term depression which was modulated by Anle138b [8]. ELK1 was again recovered, as well as STAT1, which is ...
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