Interestingly, molecular biological analyses revealed that CLL cells were of the T-cell type, whereas lymphoma cells were of the B-cell type. Chemotherapy using the L-VCA short protocol was effective for 155 days, but the dog died on day 194 after diagnosis, despite rescue therapies. 展开 ...
J. 2012. Neu- rolymphomatosis in a dog with B-cell lymphoma. Vet. Pathol. 49: 771-774. [Medline] [CrossRef]Schaffer PA, Charles JB, Tzipory L, et al. Neurolymphomatosis in a dog with B-cell lymphoma. Vet Pathol 2012;49:771-774....
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While B-cell receptor (BCR) signaling is essential for normal B-cell function, it is often deregulated and provides critical pro-survival signals for B-cell lymphomagenesis in both BL and DLBCL4,5,6,7,8. Indeed, the presence of self-antigens and/or mutations in key BCR effectors impact ...
B cell lymphomagenesis M Sochalska1, F Schuler1, JG Weiss1, M Prchal-Murphy2, V Sexl2 and A Villunger1,3 Rearrangements of MYC or ABL proto-oncogenes lead to deregulated expression of key-regulators of cell cycle and cell survival, thereby constituting important drivers of blood cancer. ...
It has been also tried in solid tumors with CD40 expression, such as diffuse large B cell lymphoma, phase I trial [147]. Another pathway was found to have a role in TAMs polarization depending on NF-κB. This pathway has a role in TAMs polarization in conjugation with TLR agonists, anti...
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<div p-id="p-0001">The present invention relates to gene expression profiles for B-cell lymphoma. More specifically, the present invention relates to gene expression profiles for diagnosis, prognosis